Bioinformatician I 40 Hours Day Bwh - Path Profile Bioinformatics

GENERAL SUMMARY/OVERVIEW STATEMENT:

The Center for Advanced Molecular Diagnostics (CAMD) is the clinical molecular diagnostics laboratory for three Harvard Medical School hospitals: Brigham and Womens Hospital DanaFarber Cancer Institute and for the pediatric cancer patients of Boston Childrens Hospital. Our mission is to provide innovative molecular and cytogenetic diagnostic services to assist with the clinical care of patients in our hospitals and affiliated clinics with a primary focus on cancer care. This is exemplified by the PROFILE program which is a collaborative effort to advance translational and personalized cancer medicine by implementing tumor genomic profiling for all cancer patients who receive care at one of the collaborating hospitals. PROFILE employs stateofthe art genomics technology to generate a detailed report of medically actionable genetic alterations in a CLIAcertified and realtime process to facilitate rapid clinical application. These cancer genomic profiles are being used to guide patient treatment and/or stratification for clinical trials of novel anticancer agents.

Working under very general supervision the Computational Bioinformatician I will have demonstrated competency is one of more of the following areas of specialization: algorithm development data analysis quality assurance/testing pipeline software/computing development user interface design & report development webbased application development Laboratory Information Management System (LIMS) development or report development as described below.

QUALIFICATIONS:

1.Minimum of 2 years of relevant experience in bioinformatics computational biology or programming/analysis working in a research and/or clinical environment working with large research datasets. Experience working in a large cancer genetics research or clinical program highly desirable.

2.Bachelors degree in bioinformatics systems or computational biology computer science or equivalent required. Advanced degree preferred.

3.Proven strong programming skills and experience in algorithm development in both Windows and Linux environments.

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

1.Excellent attention to detail

2.Excellent organizational and problem solving skills

3.Strong communication skills to be able to work effectively with multidisciplinary staff interacting with individuals at many levels of multiple institutions.

WORKING CONDITIONS:

Fast paced laboratory environment with large workload and frequent deadlines

Addendum

PRINCIPAL DUTIES AND RESPONSIBILITIES:

WEB APPLICATION DEVELOPER

Role and Responsibilities:

Working in a progressive and academic medical center the Web Application Developer will build web applications to aid in the review interpretation and sharing of genomic information. The successful candidate will play a central role in the evaluation of our current systems and the planning and development of future applications. More specifically the position will have the following responsibilities:

Maintain existing web applications for collaborator project management pathologist review & sign out of patient information and similar systems

Design and develop a knowledge base for the storage and organization of clinical interpretations for mutations found in cancer

Implement a web application for pathologists to interact with the clinical information knowledge base for generating patient reports. This system will need to integrate with the laboratory LIMS the patients electronic medical record and other enterprise wide systems.

Assist in the administration of database servers (MySQL and Microsoft SQL)

Work with crossfunctional team members to recommend technical solutions and design options to address business issues and new capabilities

QUALIFICATIONS:

Bachelors degree in Computer Science Software Engineering or related area architecture

1 years of experience with building applications in Java

Solid understanding of objectoriented design ntier architecture and MVC is required

Prior experience developing robust user interfaces using jQuery JavaScript DHTML and AJAX

Database experience with MySQL MSSQL and SQL scripting

Experience with PowerPath (Tamtron) Sunquest (Misys) Epic health information technology and integration with EMR systems is preferred

Experience in ASP 2.0 WCF MVC SQL Server Microsoft VB and .NET framework architecture would be preferred

Understanding of Cancer Biology would be preferred

Excellent verbal and written communication skills

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

Required Skills:

Solid experience in building web application using Java

Solid understanding of Object oriented Concepts web application development MVC architecture

Willingness to learn new technologies on the job

Experience working in a highpaced environment

Detail oriented analytical and problemsolving mindset

Current with emerging Web Technologies