drjobs Postdoctoral Researcher

Postdoctoral Researcher

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1 Vacancy
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Job Location drjobs

Edinburgh - UK

Yearly Salary drjobs

£ 40497 - 48149

Vacancy

1 Vacancy

Job Description

Description

Grade UE07:per annum

CMVM/MRC Human Genetics Unit

Fulltime: 35 hours per week (we are open to considering flexible working patterns)

Fixedterm: until 31 May 2027

The Opportunity:

Our research is focused on understanding how genetic changes in the noncoding genome can impact gene regulatory mechanisms alter developmental processes and ultimately affect human craniofacial shape and function in health and disease. In this project we are interested to investigate changes to gene regulatory landscapes across development as facial progenitor cells differentiate into skeletal celltypes. You will utilise in vitro models of facial development and leverage a combination of cuttingedge epigenomic methods genome editing and synthetic biology approaches to gain fundamental insights into mechanisms of gene regulation and human disease biology.

Your skills and attributes for success:

  • Interest in mechanisms of gene regulation and enhancer biology in development and disease.
  • Experience in generating and analysing epigenomic and transcriptomic datasets (e.g. ChIPseq ATACseq CUT&RUN 3Cbased methods RNAseq etc) cell culture in vitro differentiation methods and genetic engineering (preferable but not essential).
  • Ph.D. (or near completion) in a relevant science subject.
  • Proven track record of publication in peerreviewed journals.
  • Strong communication and collaboration skills.



Employment Type

Full-Time

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