Scientist Molecular and Cell Biology
Scientist Molecular and Cell Biology
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$ 138250 - 141750
1 Vacancy
Job Description
Description
Job Title:
Scientist Molecular and Cell Biology
Location:
La Jolla California
Position type:
FLSA:
Full Time
Exempt
Department:
Finance ID:
Technical Development and Operations 7625Q22416
Profoundly Improve Peoples lives by Revolutionizing the Delivery of RNA Therapeutics
At Avidity Biosciences we are passionate about the impact of every employee in realizing our vision of improving peoples lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed solutionoriented thinker join us in making a difference and become part of our growing culture that is integrated collaborative agile and focused on the needs of patients.
Avidity Biosciences Inc.s mission is to profoundly improve peoples lives by delivering a new class of RNA therapeutics Antibody Oligonucleotide Conjugates (AOCs). Utilizing its proprietary AOC platform Avidity demonstrated the firstever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1 Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered inSan Diego CA.For more information about our AOC platform clinical development pipeline and people please visit www.aviditybiosciences and engage with us on LinkedIn and X.
The Opportunity
As Avidity transitions from late stage clinical to commercial operations an effective quality control strategy will be critical to ensuring the safety efficacy and reproducibility of our drug products. To facilitate these efforts we are seeking a Scientist to join the Analytics group with experience in developing and optimizing robust cellbased assays for later phase clinical programs. The position will also support preclinical development of secondgeneration AOC therapeutics. This is a unique opportunity and will enable the individual to interact with multiple departments including Chemistry Biology and Bioanalytical Sciences. This individual will work in a highpaced matrix environment and must be able to communicate and collaborate between them effectively.
What You Will Contribute
Creative and independent assay design skills
A solid and independent understanding of molecular biology workflows to design and create fluorescence and luminescentbased cell reporter assays.
Experience with molecular pharmacology principles used to characterize ligand receptor interactions
Wetbench efforts towards analytical assay and validation
Method and SOP development optimization (including DOE) and documentation
CRO management to support early and late phase GMP release testing.
Hands on experience with cell line development and engineering (viral and/or CRISPR)
An understanding of FDA regulations related to GMP analytical testing including USP and ICH guidance
A positive cando attitude that thrives working as a part of a highly efficient team
What We Seek
A PhD in biology pharmaceutical sciences bioengineering or equivalent
1 2 years of pharmaceutical experience or 3 5 postdoctoral and industry experience
Experience with cell and molecular pharmacology and assay development.
Proven ability to thrive and enable success in a crossfunctional and collaborative environment.
Excellent communication and interpersonal skills and the ability to facilitate constructive and expedient problemsolving.
Ability to multitask manage conflict and work in a fastpaced environment.
R or pythonbased data wrangling skills to facilitate data analysis workflows (preferred but not required)
What We Will Provide To You
The base salary range for this role is $138250 $141750.The final compensation will be commensurate with such factors as relevant experience skillset internal equity and market factors.
Avidity offers competitive compensation and benefits which include the opportunity for annual and spot bonuses stock options and RSUs as well as a 401(k) with an employer match. In addition the comprehensive wellness program includes coverage for medical dental vision and LTD and four weeks of time off.
A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees opportunities for jobspecific training offered by industry and an education reimbursement program.
Avidity Biosciences
10578 Science Center Dr. Suite 125
San Diego CA
92121
O:
F:
Employment Type
Full-Time
