RD Scientist - Molecular Assay Development
RD Scientist - Molecular Assay Development
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
R&D Scientist Molecular Assay Development
Genepika is dedicated to advancing geneticsrelated research engineering and product development. Innovations in the field of molecular biology over recent decades have revolutionized the capabilities of genetic tools available to researchers. Applications such as gene editing and drug discovery have extensively explored the potential of nucleic acidbased technology for advancing healthcare. One promising application for genetic tools is the development of novel molecular diagnostic devices significantly accelerated by the onset of the COVID19 pandemic. The widespread authorizations of pointofcare (POC) diagnostic platforms has demonstrated their importance in resourcescarce settings and in streamlining clinical services. Clinical data shows that early detection of viral infections via POC diagnostic can greatly improve treatment success rates despite these devices having lower sensitivity and accuracy compared to traditional laboratory diagnostics. Although scaled manufacturing of complex POC diagnostic devices remains challenging there is an opportunity to develop more scalable molecular platforms to increase the public access to these technologies.
At Genepika we believe it is crucial to improve the public reception and more importantly understanding of these molecular technologies and their capabilities. Therefore we are committed to building a new generation of molecular diagnostic devices for consumer applications bringing the benefits of rapid diagnostics to everyday life. We are seeking an R&D Scientist with extensive experience in developing molecular assays for diagnostic applications to join our founding team. As an R&D Scientist you will be responsible for developing molecular assays for portable diagnostic devices. The role will focus on running experiments to optimize assay performance to meet design objectives. Once completed they will be working with other team members to integrate the assay onto a portable diagnostic device.
Required Qualifications
- MSc with 12 years of relevant work experience (including academic institutions) or PhD with relevant thesis topics
- Handson experience with diagnostic assay development and optimization.
- Experience with both antigenbased diagnostic assays as well as DNA/RNAbased molecular assays; ideal candidates should have worked on projects developing both types of assays for diagnostic applications
- Able to design and conduct experiments to meet development objectives with minimal supervision
- Thorough understanding of fundamentals behind antigenbinding kinetic competitivebinding assays and various nucleic acid amplification methods
- Understanding of chemistry behind different modalities for diagnostic signal output such as colorimetric or fluorescence
- Have previous experience working with complex sample matrices and sample processing techniques
- Have previous experience creating and testing custom formulations for different sample buffers
- Demonstrated excellence in data analysis and research communication through academic publication record and conference presentations
Preferred Qualifications
- Previous industrial experience developing diagnostic assays
- Working knowledge of industrialscale antibody and nucleic acid production
- Working knowledge of microfluidic principles and lateral flow devices
- Familiar with laboratory equipment calibration
- Familiar with regulatory requirements of diagnostic devices
- Familiar with ISO13485 standards
Other Requirements
- This is an inperson position; candidate must be able to travel to lab location
- Must be able to adapt quickly to changing priorities in a startup environment
Employment Type
Full-Time
