Precision Medicine Therapeutic Area TA Lead- Obesity

Career Category

Job Description

HOW MIGHT YOU DEFY IMAGINATION

If you feel like youre part of something bigger its because you are. At Amgen our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching manufacturing and delivering everbetter products that reach over 10 million patients worldwide. Its time for a career you can be proud of.

Precision Medicine Therapeutic Area Lead

Live

What you will do

Lets do this. Lets change the world. In this vital role you will act in conjunction with the Obesity Therapeutic Area head to advance the development and of Precision Medicine objectives. Lead a crossfunctional team to develop and execute translational and precision medicine strategies to support asset (and aboveasset as needed) development across the product lifecycle. Additionally partner with cross functional Therapeutic Area leads across Research & Development to guide the development of translational reverse translational and precision medicine strategies.

• Serve as the strategic integrator of various stakeholder inputs and multiple lines of evidence for the development of translational medicine and precision medicine strategies at asset and/or indication level.
• Set strategic vision to enhance the value of the asset across the product lifecycle through clinical biomarker target identification indication selection early indication of biological activity and patient stratification/selection including reverse translation strategies.
• Course correct as needed by incorporating deep mechanistic insights and omics signatures into actionable precision medicine strategies.
• Lead crossfunctional teams in the development and of phase appropriate integrated biomarker and human data plans to support translational pharmacology and inform patient selection strategies.
• Serve as the key liaison between research and development by providing clinical translational considerations (proof of target engagement dose selection patient selection) to inform discovery asset development as well as enabling reverse translational strategies (to gain mechanistic insights related to patient stratification response/resistance) for assets in clinical phase.
• Provide precision medicine considerations to shape disease area strategies (disease endotypes indications and combinatorial approaches). Provide subject matter expertise to inform registrational and access and use evidence generation plans.
• Work crossfunctionally to evaluate appropriate data sources and strategies for translational/precision medicine and propose funding/collaboration needs to appropriate Commercialization Governance Forums.

Win

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of relevant experience

OR

Masters degree and 7 years of relevant experience

OR

Bachelors degree and 9 years of relevant experience

Preferred Qualifications:

• MD & PhD with 6 years industry & academic experience
• Deep scientific and analytical expertise in integrating multiple data sources e.g. omic clinical Real world evidence (RWE) to inform precision medicine approaches
• Strong professional network with external Key Opinion Leaders academic institutions and industry partners
• Experience in translational research and/or advancing clinical candidates
• Knowledge of Good Clinical Practices (GCP) and applicable regulatory requirements for biomarker and diagnostic development
• Proven ability to lead manage and motivate others in a complex multifunctional matrix environment
• Exceptional leadership and team management skills

Thrive

What you can expect of us

As we work to develop treatments that take care of others we also work to care for our teammates professional and personal growth and wellbeing.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities including:

• Comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts.
• A discretionary annual bonus program or for field sales representatives a salesbased incentive plan
• Stockbased longterm incentives
• Awardwinning timeoff plans and biannual companywide shutdowns
• Flexible work models including remote work arrangements where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race color religion sex sexual orientation gender identity national origin protected veteran status or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation

#obesity

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