Associate Scientist II Polysaccharide Process Development
Associate Scientist II Polysaccharide Process Development
Posted on :
15-03-2025
Employer Active
1 Vacancy
The job posting is outdated and position may be filled
Job Alert
You will be updated with latest job alerts via emailValid email field required
Send jobs
Share
Send me jobs like this
Job Alert
You will be updated with latest job alerts via emailValid email field required
Send jobs
Monthly Salary
$ 105000 - 114500
Vacancy
1 Vacancy
Posted on :
15-03-2025
Job Description
Join our Mission to Protect Humankind!
Vaxcyte is a clinicalstage vaccine innovation company engineering highfidelity vaccines to protect humankind from the consequences of bacterial diseases which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease Group A Strep periodontitis and Shigella is just the beginning. Our path to success is clear and welldefined and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it!Our work together is guided by four enduring core values:
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindnessfirst inclusive approach to collaboration and vigorous debate that advances our business objectives.
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and reinnovate the way vaccines are delivered.
*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity accountability equality and clarity across communications and decision making.
Summary:
The Development organization is comprised of four Process teams: Protein Polysaccharide Conjugate Drug Substance (Conjugation) and Drug Product. These Process Development teams are supported by Analytical Development and Formulation Development teams. Vaxcyte is looking for an Associate Scientist II with experience in microbial fermentation and upstream processing to join the MFG/Process Development Team. The candidate will be responsible for collaboration on experimental design and of experiments to further develop and optimize upstream processes for polysaccharide manufacturing. The successful candidate will have practical laboratory experience related to upstream processes and eager to utilize and learn new laboratory skills. The role will require >50 time in the lab and this person will be able to independently detail experimental procedures/results in written and presentation formats. The successful candidate may interface closely with the crossfunctional team write detailed technical reports present experimental results internally and may potentially interface with external CMO partners.
Essential Functions:
- Assist in designing and executing process development runs focusing on scale down modeling and latestage process characterization of upstream and primary recovery steps.
- Operate and maintain instrumentation including TFF systems depth filtration and continuous centrifugation.
- Record data in electronic laboratory notebooks and aid in writing technical summary reports.
- Perform analytical assays for process development and inprocess manufacturing samples and maintain manufacturing and process development data repositories.
- Perform statistical analysis for manufacturing inprocess data for manufacturing process insights and characterization purposes.
- Present data to the team to provide updates on small scale development activities and contribute to technical discussions.
- Review manufacturing documents and transfer inprocess data to data repositories.
Requirements:
- B.S./M.S. in biochemistry bioengineering chemical engineering or other related disciplines with 2 years of experience.
- Prior experience with fermentation and primary recovery operations including depth filtration centrifugation and TFF.
- Experience with analytical methods such as platebased assays UVspectrophotometry and metabolite analyzers.
- Experience writing technical documents including lab operation protocols and data summary reports.
- Proficiency in computer programs including Microsoft Excel Word and Powerpoint.
- Experience with statistical software such as JMP R studio python etc. for data analysis.
- Familiarity with statistical methods for process characterization and validation is a plus.
- Familiarity with DOE principles and experience with DoE software (JMP) is a plus.
- Experience with GXP requirements including deviation investigations CAPAs and change controls is a plus.
Reports to: Senior Engineer Polysaccharide Process Development
Location: San Carlos CA
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $105000 $114500
Vaxcyte Inc.
825 Industrial Road Suite 300
San Carlos CA 94070
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race color religionsex sexual orientation gender identity national origin disability or veteran status.
Required Experience:
IC
Employment Type
Full-Time
Report This Job
Disclaimer: Drjobpro.com is only a platform that connects job seekers and employers. Applicants are advised to conduct their own independent research into the credentials of the prospective employer.We always make certain that our clients do not endorse any request for money payments, thus we advise against sharing any personal or bank-related information with any third party. If you suspect fraud or malpractice, please contact us via contact us page.
