China Precision Medicine-PathologistPathology Lab Leader

Job Description:

As China Precision Medicine-Pathologist/Pathology Lab Leader you will provide expertise in human disease pathology experimental pathology support and contribute to the development and interpretation of tissue-based assays across therapeutic areas. You will also be responsible for pathology lab/team setup project management data analysis and interpretation of pathology lab testing results.

Key Responsibilities:

Specific responsibilities can include:

• Lead China pathology lab/project development teams or sub-teams. Coordinate with appropriate team members to advance projects efficiently. Focus of the position will be to provide pathology support needed for spatial biology and single cell genomics.
• Contribute to or Lead the design and interpretation of tissue-based studies investigating aspects such as target biology drug MOA target pathway activation pharmacodynamic effects biomarker prevalence or drug distribution.
• Contribute to the design validation and deployment of pathology assays including the determination of assay parameters such as specificity and sensitivity. Design implement and oversee pathology-based biomarker and diagnostic testing including data analysis:
• Develop validate and implement scoring paradigms for tissue-based assays
• Direct the development outsourcing and validation of clinically applicable tissue-based assays. Assist in the development of assay protocols as needed.
• Provide pathology input to project teams and ensure access to state-of-the-art tissue-based techniques and samples for target pathway evaluation in human disease:
• Implement technologies and/or methodologies via a combination of in-house efforts and the use of CROs or other external expertise using techniques such as in situ hybridization immunohistochemistry (including multiplexed) spatial biology image analysis etc.
• Evaluate the scientific basis and clinical applicability of the proposed assays their validation status and any related technical issues.
• Assume responsibility for the assessment and scoring of specimens and the preparation of reports summarizing the data analysis and interpretation of findings.
• Write the relevant pathology-based biomarker and diagnostics testing sections in drug development and registration documents such as clinical study protocols clinical study reports investigator brochures and regulatory submission packages (INDs NDAs BLAs).
• Collaborate with project teams from concept to reagent generation to quantitation and approval plan for CDx as needed.
• Participate in the evaluation of external licensing or collaborative opportunities (including CDx collaborations) and oversee internal components of shared programs.

Qualifications :

• Experienced pathologist (MD) or PhD with relevant post-doctoral academic clinical and/or industry pathology experience -required
• Board certification in pathology (anatomic clinical combined with or without additional specialization) preferred
• Proven track record with pathology lab/team/project leadership and pathology assay development/validation
• Research experience with spatial biology or multiplex IHC/IF preferred

Additional Information :

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time