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Lead AI Architect

McKesson


Job Location:

Mississauga - Canada

Yearly Salary: CAD 122100 - 162800
Posted: 1 October 2026 (Yesterday)
Application Deadline: 29 December 2026
Vacancies: 1 Vacancy

Job Summary

McKesson is an impact-driven Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights products and services that make quality care more accessible and affordable. Here we focus on the health happiness and well-being of you and those we serve we care.

What you do at McKesson matters. We foster a culture where you can grow make an impact and are empowered to bring new ideas. Together we thrive as we shape the future of health for patients our communities and our people. If you want to be part of tomorrows health today we want to hear from you.

We are seeking a Lead AI Architect to define and guide enterprise-grade architecture for AI-enabled mission-critical products and this role you will translate business strategy into scalable solution designs approve end-to-end AI architectures and help teams operationalize AI/ML capabilities securely and responsibly. You will partner across engineering data security and business teams to shape target-state architecture simplify the technology landscape and deliver measurable outcomes in a regulated enterprise environment.

What Youll Do

  • Design and approve end-to-end AI data and application architectures for enterprise platforms and high-impact initiatives.

  • Lead AI/ML lifecycle operationalization including deployment readiness observability and ongoing optimization.

  • Define architecture standards governance guardrails and exception processes that support security reliability performance compliance and operability.

  • Guide cloud-native and hybrid solution strategy across cloud platforms with Azure AI Foundry preferred.

  • Direct data preparation and feature engineering approaches that support scalable production-ready AI solutions.

  • Evaluate platforms integration patterns APIs event-driven architectures and data flows to align current-state systems to target-state roadmaps.

  • Partner with product engineering security and operations leaders to manage technical risk accelerate delivery and communicate trade-offs to technical and non-technical stakeholders.

  • Mentor architects and engineers while promoting modern ways of working continuous improvement and enterprise systems thinking.

Minimum requirements: Degree or equivalent and typically requires 10 years of relevant experience. Less years required if has relevant Masters or Doctorate qualifications.

Basic Requirements

  • 10 years of experience in solution architecture enterprise architecture software engineering or a related technical discipline.

  • Bachelors degree in Computer Science Engineering Information Systems or a related field or equivalent experience.

  • Proven experience designing enterprise-scale architectures for cloud-based distributed and integrated systems.

  • Demonstrated experience with AI/ML architecture AI/ML lifecycle operationalization and production deployment patterns.

  • Hands-on knowledge of cloud architecture; experience with Microsoft Azure required with Azure AI Foundry strongly preferred.

  • Experience defining and enforcing architecture governance standards and design review processes.

  • Strong knowledge of APIs event-driven integration data architecture security-by-design and operational resilience.

  • Ability to communicate architecture decisions risks and trade-offs clearly to executive and cross-functional audiences.

Preferred Skills / Experience

  • Experience with TOGAF C4 model ITIL 4 OWASP Top 10 or similar enterprise architecture and security frameworks.

  • Experience with multi-cloud environments CI/CD infrastructure as code observability backup/disaster recovery and high-availability patterns.

  • Background in data preparation feature engineering MLOps model monitoring and AI governance.

  • Experience supporting regulated complex or large-scale enterprise environments.

  • Track record of leading modernization initiatives portfolio roadmaps or M&A-related architecture integration.

  • Experience influencing across domains and coaching architects or engineering teams.

Work Environment

  • Hybrid role requiring 2 days per week in-office at either our Ville Saint-Laurent (QC) or Mississauga (ON) location.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors including performance experience and skills equity regular job market evaluations and geographical markets. The pay range shown below is aligned with McKessons pay philosophy and pay will always be compliant with any applicable regulations. In addition to base pay other compensation such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson pleaseclick here.

Our Base Pay Range for this position

$122100 - $162800

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKessons (or affiliated entities like CoverMyMeds or RxCrossroads) name in fraudulent emails job postings or social media light of these scams please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: .

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability age genetic information or any other legally protected category. For additional information on McKessons full Equal Employment Opportunity policies visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment please contact us by sending an email to (United States) or (Canada) . Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!


Required Experience:

Staff IC


About Company

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McKesson is the leading healthcare company for wholesale medical supplies & equipment, pharmaceutical distribution, and healthcare technology solutions. McKesson is the central nervous system of health care. At any given moment, in any given minute, we simultaneously execute thousands ... View more

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