Bioinformatics Analyst

Union: Non-Union
Number of Vacancies: 1
New or Replacement Position: Replacement
Site: Princess Margaret Cancer Centre
Department: Research
Reports to: Senior Scientist
Salary Range: $68932 - $103409 Per Year
Hours: 37.5 Hours Per Week
Shifts: Day shifts
Status: Temporary Full-time
Closing Date: June 12 2026

Position Summary:
We are seeking an enthusiastic and highly motivated full-time Bioinformatics Analyst to join our team initially on a contract basis with the possibility of transition to a permanent position. Our lab focuses on understanding how the bone marrow microenvironment shapes hematopoiesis and leukemia with a strong emphasis on single-cell and spatial approaches. The successful candidate will lead the computational analysis of single-cell RNA-seq spatial transcriptomics and T cell receptor (TCR) sequencing datasets with a particular focus on integrating cellular states clonal architecture and spatial organization.

This is a highly collaborative research environment with access to unique human datasets and ongoing projects in leukemia and bone marrow biology. The position offers the opportunity to work at the interface of computation and biology and to contribute to high-impact studies.

Duties:

• Analyze and interpret single-cell RNA-seq spatial transcriptomics and TCR sequencing data
• Integrate multi-modal datasets including scRNA-seq spatial transcriptomics TCR sequencing and imaging data
• Perform cell-cell interaction niche and clonotype analyses
• Link T cell clonality with transcriptional states
• Collaborate closely with experimental team members to guide study design and data interpretation
• Contribute to manuscripts and collaborative research projects

Qualifications :

• Masters degree in computational biology Bioinformatics or a related field
• Experience with single-cell data analysis using Seurat Scanpy or similar tools
• Experience with TCR/BCR analysis is highly desirable
• Strong programming skills in R and/or Python
• Results-driven with a strong sense of ownership and the ability to efficiently advance analyses and projects
• Ability to work independently as well as collaboratively within a multidisciplinary team

Additional Information :

Why join UHN

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts on-site gyms etc.)

Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest however only those selected for further consideration will be contacted.

Remote Work :

No

Employment Type :

Full-time