Principal Solution Architecture AI Native Drug Disc

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Principal Solution Architect - AI Native Drug Discovery

We are seeking a Technical Solution Architect to join our Solution Architecture organization. This role will be instrumental in designing and delivering critical components of an end-to-end AI-native drug discovery engine a pivotal initiative redefining how differentiated therapies are discovered.

The architect will operate within a scalable fit-for-purpose end-to-end technology stack supporting a DesignMakeTestLearn (DMTL) closed-loop system using AI automation and proprietary data to accelerate discovery outcomes.

The impact of this role is significant and far-reaching directly contributing to the transformation of drug discovery through advanced technology and data-driven innovation. By designing and enabling key components of the AI-native discovery engine!

Key Responsibilities

• Solution & Component Architecture. Design and govern modular solution architectures ensuring seamless data and workflow integration. Define integration patterns across platforms such as LIMS SDMS data platforms and AI/ML systems
• Data & AI Architecture Enablement. Architect solutions enabling closed-loop data generation and feedback cycles across discovery workflows. Support design of AI-ready data pipelines ensuring data quality lineage and accessibility and enable integration of AI/ML models and agentic tools into discovery processes
• Integration & Platform Engineering. Lead architecture for systems integration across lab automation laboratory systems and enterprise platforms define patterns for event-driven workflows orchestration and observability in automated discovery pipelines. Collaborate with engineering teams (cloud data ML Ops) to deliver robust scalable solutions
• Collaboration with Scientific & Engineering Teams. Partner with scientists data engineers AI researchers and lab automation teams to translate scientific workflows into technical -design solutions that enable AI-augmented science and decision intelligence
• Governance Security & Compliance. Ensure architectures align with cybersecurity data governance and regulatory standards. Embed secure-by-design principles particularly in the context of AI and sensitive discovery data

Required Qualifications

Experience

• 5 years in solution architecture platform architecture or systems integration
• Proven experience delivering complex distributed data-driven platforms
• Experience in life sciences / pharma R&D environments (preferred)

Technical Expertise

Strong background in:

• Cloud-native architectures and distributed systems
• API-led and event-driven integration patterns
• Data platforms (e.g. Snowflake or equivalent AI-ready data systems)

Familiarity with:

• AI/ML platforms and MLOps ecosystems
• Laboratory systems (LIMS SDMS) and lab automation environments
• Data engineering and ingestion pipelines

Domain Knowledge (Preferred)

• Understanding of drug discovery workflows (DesignMakeTestLearn)
• Awareness of automation in laboratory environments and data generation pipelines

Key Competencies

The candidate demonstrates strong systems thinking with the ability to design solutions across complex and highly interconnected domains. They bring deep expertise in abstraction and modular design enabling the creation of scalable component-level architectures that integrate seamlessly into broader platforms. The role requires excellent engagement skills fostering effective collaboration across scientific and technical teams to translate complex requirements into actionable solutions. Appetite for innovation is essential with comfort in working with emerging AI and automation technologies combined with a clear execution focus to deliver high-impact results within bold timelines.

What we offer:

The opportunity to work on high-impact initiatives in a world-class healthcare organization improving experiences for patients customers and colleagues. A collaborative supportive environment where your architecture skill and curiosity are valued.

Bring your architecture craftsmanship to a mission that matters and help us build technology and services that improve care for patients and customers across the world.

Required Skills:

Preferred Skills:

The anticipated base pay range for this position is:

Benefits:

In addition to base pay we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location where the actual amount is based on the employees and companies performance of the previous calendar year or sales commissions. Moreover we offer vacation days parental leave for a minimum of 12 weeks bereavement leave caregiver leave volunteer leave well-being reimbursement programs for financial physical and mental health. We also offer service anniversary and recognition awards and subject to the terms of their respective plans employees - and in some locations eligible dependents - can participate in several insurance plans. For more information visit Employee benefits Supporting well-being & career growth Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.