Data Scientist–Agentic Bioinformatics

Bioinformatics & AI Expertise Unit

VIBKU Leuven Center for Cancer Biology (CCB) Leuven Belgium

The VIBKU Leuven Center for Cancer Biology (CCB) is a leading research institute focused on understanding cancer biology and developing innovative therapies. Our Bioinformatics & AI Expertise Unit provides advanced computational support to multiple research groups within CCB (Learn more: Bioinformatics & AI).

We are seeking an Data Scientist with a background in bioinformatics or computational biology to explore build and deploy tools based on large language models (LLMs) that support research at CCB. This includes agentic workflows that help researchers find suitable methods write and run analysis code and work with multiomics and spatial data. You will critically evaluate these tools bring the useful ones into daily use across research groups and help the CCB community use them effectively and responsibly.

You will join a growing team led by Dr. Masoomeh Rahimpour and work closely with the Integrative Cancer Genomics lab of Prof. Jonas Demeulemeester other CCB Expertise Units and the ML Unit of the VIB Center for AI & Computational Biology (Learn more: ).

• Build LLM-based tools and agentic workflows for bioinformatics tasks such as assistants that help run and document standard analyses retrieval over internal protocols and documentation.
• Connect LLM tools to existing bioinformatics resources including our pipelines HPC environment databases and public resources (e.g. via tool calling or MCP).
• Evaluate the reliability of these tools on realistic research tasks with attention to correctness reproducibility and data privacy.
• Deploy and maintain tools for CCB researchers in collaboration with the ML Unit at and the Vlaams Supercomputer Centrum (VSC).
• Stay up to date with stateoftheart methods in LLMs AI agents and computational biology; evaluate benchmark and introduce relevant tools and best practices.
• Deliver training and workshops on the practical and responsible use of LLMs and AI tools in research.

We welcome applications from all backgrounds and career paths. If this role interests you and you meet most of the essential requirements we encourage you to apply.

• A PhD in Bioinformatics Computational Biology Computer Science or a related field or equivalent professional experience (e.g. in industry).
• Strong programming skills in Python.
• Hands-on experience with LLMs (via APIs or open-weight models) for example prompt design or tool/function calling.
• Working knowledge of common bioinformatic workflows (e.g. sequencing single-cell or spatial data) enough to judge whether an AI-generated analysis makes sense.
• Ability to explain AI concepts and their limitations clearly to non-specialists.
• Willingness to keep learning and to share knowledge with colleagues.
• Good communication skills in English.

Nice to have:

• Experience with retrieval-augmented generation (RAG) over scientific literature or internal documentation.
• Experience with agent frameworks (e.g. LangGraph or similar).
• Experience running open-weight models on local or HPC hardware.

• Access to unique datasets and cutting-edge infrastructure.
• A collaborative and international research environment.
• Support for your personal and professional development through training mentoring and career development.
• A salary in line with VIB salary scales based on your experience and a benefit package.
• A full-time indefinite contract with flexible working hours.

Please complete the application through the CCB online application tool. Your application should include:

• A motivation letter explaining your interest in the role and how your experience relates to it.
• Your CV.
• Contact information of three references (we only contact references of shortlisted candidates).

Application deadline: 30 November 2026

For inquiries contact with subject line: Data Scientist - Agentic Bioinformatics