VP, Clinical Development

About Absci

Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation platform combines cutting-edge AI models with a synthetic biology data engine enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.

Absci is a global company headquartered in Vancouver WA and maintains offices in New York City Switzerland and Serbia. Learn more at or follow us on LinkedIn (@absci) X (@Abscibio) and YouTube.

Vice President Clinical Development

Remote Vancouver WA or New York NY

About the role:

Reporting to the Chief Medical Officer (CMO) the Vice President Clinical Development provides executive leadership for the companys clinical research and development activities including Abscis proprietary biologics programs and partner-developed therapeutics leveraging our synthetic biology and AI-driven protein engineering platform. The Vice President is responsible for the strategic planning execution and oversight of clinical development strategies that support Abscis transition from platform provider to integrated biotherapeutics company.

The Vice President Clinical Development serves as a senior leader within Clinical Development accountable for clinical trial design execution regulatory strategy data integrity and cross-functional alignment across internal programs and external partnerships. The role partners closely with our Protein Engineering Bioinformatics Clinical Operations Regulatory Affairs and Drug Safety teams to ensure clinical programs leverage Abscis differentiated platform capabilities while meeting regulatory requirements and medical standards. The Vice President Clinical Development contributes to portfolio-level decision-making and represents Clinical Development in internal governance forums external partnerships and investor engagements.

Responsibilities:

Clinical Strategy & Execution

• Provide executive both senior-level oversight and hands-on leadership for the design planning and execution of clinical development programs for Abscis proprietary therapeutic candidates and select partner-developed programs utilizing our platform.
• Lead the development and implementation of clinical development plans aligned with Abscis product strategy registration pathways and platform-enabled lifecycle management objectives.
• Ensure high-quality execution of clinical trials including protocol development data collection analysis and reporting in compliance with GCP regulatory and medical standards.
• Oversee preparation and review of key clinical documents including protocols Investigators Brochures clinical study reports and regulatory submission materials.
• Translate Abscis platform-derived insights (protein engineering sequence design data) into clinical development strategy and biomarker/pharmacology rationale.

Organizational & Cross-Functional Leadership

• Serve as a senior Clinical Development representative on cross-functional project teams governance committees and internal review bodies.
• Partner with Clinical Operations and external CROs to ensure efficient trial execution appropriate medical monitoring and adherence to safety and quality standards.
• Together with Clinical Operations build and maintain relationships with key stakeholders including investigators site staff and key thought leaders. Absci expects Clinical Development and Clinical Operations teams to visit our sites and maintain strong relationships with these important partners
• Collaborate with Drug Safety to ensure ongoing evaluation of safety data and integration of pharmacovigilance considerations into clinical programs.
• Work closely with Protein Engineering and Bioinformatics internal and external cross-functional teams to ensure clinical development strategy leverages platform-generated molecular and functional insights.
• Contribute to enterprise decision-making through participation in portfolio reviews partnership evaluations investment discussions and development governance forums.
• Responsible for effectively communicating program goals strategies plans issues and risks with team members department heads review boards and the executive leadership team

Regulatory & Partnership Engagement

• Support interactions with global Health Authorities by contributing to briefing packages responses and strategic positioning for assigned programs.
• Lead clinical development due diligence and strategy for potential in-licensing partnering or acquisition opportunities that would utilize Abscis platform.
• Engage with external experts investigators key opinion leaders and advisory boards to inform clinical strategy and execution.
• Represent Abscis clinical development capabilities to existing and potential pharmaceutical and biotech partners evaluating platform collaborations.
• Play a leadership role in steering committee and independent data monitoring committee presentations and interactions

Strategic Contribution

• Translate emerging clinical and platform-generated data into actionable insights to inform development decisions and portfolio strategy.
• Support the CMO in shaping long-term clinical development capabilities processes and talent as Absci expands its proprietary pipeline.
• Contribute to external visibility and thought leadership through presentations and publications demonstrating the clinical application of Abscis synthetic biology Platform.

You Will Be Successful If You:

• Bring knowledge and experience leading or supporting interactions with global Health Authorities and contributing to regulatory strategy
• Demonstrate ability to evaluate interpret and communicate complex scientific and clinical data to inform development and portfolio decisions
• Bring thorough knowledge of Good Clinical Practice statistics and clinical trial design
• Working understanding of synthetic biology protein engineering bioinformatics or platform-driven drug development approaches
• Proven executive-level leader with experience driving clinical development strategies and delivering high-quality outcomes across multiple stakeholders
• Significant experience working cross-functionally within a matrixed organization and establishing productive scientific partnerships with external experts and collaborators
• Excellent executive communication (verbal and written) and presentation skills with the ability to influence internal and external stakeholders
• Ability to communicate complex platform science and technical capabilities to non-scientific audiences (investors partners board)
• Ability to travel domestically and internationally (up to 25 to 30%)

Education & Experience

• M.D. or M.D./Ph.D. degree ; advanced knowledge in immunology protein therapeutics oncology or related areas relevant to Abscis focus areas
• 8 years of experience in clinical research including the design and execution of clinical trials (Phases 1-4) within a pharmaceutical or biotech environment; 5 years leadership experience
• Minimum of 8 years of experience in clinical research or drug development (Phase 1 through 3) in an academic biotech or industry environment; 6 years in a biotech/pharmaceutical setting
• Preferred experience with biologics (monoclonal antibodies protein therapeutics cell therapy) and/or platform-based drug development models
• Experience with clinical development in smaller biotech settings and managing partnerships or in-licensed programs

Preferred (but not required):

• Track record of successfully advancing clinical programs through IND or CTA various stages of clinical development filings
• Experience in therapeutic areas relevant to Absci (oncology immunology protein therapeutics dermatology womens health immunology)

How We Thrive Together: Abscis Core Values

• We Believe in the Impossible
• We are one team with one finish line
• We embrace our differences
• We deliver Results
• We do the right thing
• Innovate because lives depend on it.

Compensation and Benefits

The salary range for this position is $355K - 390K/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law

Absci offers highly competitive salaries and benefits including medical dental vision insurance unlimited vacation parental leave employee assistance program voluntary life and disability insurance annual bonus potential and 401(k) with a generous company match.

Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex sexual orientation gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information marital status or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact .