Upstream Process Development Associate III
Job Location:
Durham, NC - USA
Monthly Salary:
Posted on:
Vacancies:
Job Summary
Position Summary:
KBI Biopharma seeks to fill a role for Upstream Cell Culture Process Development Associate. This person will lead and assist in cell culture and harvest projects for mammalian cell lines (mainly CHO variants) in support of process development scale-up and technology transfer to cGMP manufacturing.
Position Responsibilities:
Assist the team in the set-up operation and associated analysis of cell culture and bioreactor processes including bioreactor preparation autoclaving inoculation sampling feeding data entry and data analysis for shake flask and various scale bioreactors (ambr15 ambr250 3 L & 15 L glass bioreactors 50 L and 200 L Xcellerex single-use bioreactors).
Lead in maintaining and monitoring process development experiments in shake flasks and bioreactors. Required to perform calculations for growth rate specific productivity and bioreactor agitation and gassing scale up/scale down.
Perform data entry and plotting generate presentations and support writing of technical reports using MS Office (Excel PowerPoint and Word).
Maintain detailed batch sheets and data binders with shake flask and bioreactor test results following good documentation practices (GDP).
Assist in data analysis using statistical software like Design Expert (DOE) JMP etc. and help with writing technical documents and reports.
Maintains a cell culture-specific project plan including raw materials and equipment availability in preparation of laboratory and pilot- scale runs.
Serves as a participant on process development teams and coaches junior individuals on cell culture techniques.
If necessary interacts with client to present data provide responses to client queries and help take projects from start to finish either independently or in teams of 2-3 individuals.
Assist in process transfer from process development to manufacturing.
Experience in medium development will be a plus
Position Requirements:
Bachelors and 1-3 years experience or masters degree and 2 years experience in Chemical Engineering Biotechnology or related area.
Working knowledge of mammalian cell culture.
Advanced ability with Microsoft Office (Excel PowerPoint and Word).
Demonstrates ability to work both independently and as a member of a team.
Excellent customer service skills and the ability to meet strict client deadlines.
Flexibility of hours to support cell culture processes over weekends (2-4 weekend days per month) and holidays. Weekend and holiday hours are compensated as a premium in addition to base salary.
Salary: $50000-$70000
Salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidates qualifications and experience and may be outside this range. KBI has a robust total rewards strategy which includes an annual bonus structure for all employees medical dental and vision coverage paid PTO and holidays Sabbatical program 401K matching with 100% vesting in 60 days and employee recognition programs.
KBI Biopharma Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore all qualified applicants regardless of race color national origin religion gender gender identity sexual orientation age disability or veteran status are strongly encouraged to apply.
I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma Inc. to hire me. If I am hired I understand that either KBI Biopharma Inc. or I can terminate my employment at any time and for any reason with or without cause and without prior notice. I understand that no representative of KBI Biopharma Inc. has the authority to make any assurance to the contrary.
I attest with my signature below that I have given to KBI Biopharma Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma Inc. to contact references provided for employment reference checks. If any information I have provided is untrue or if I have concealed material information I understand that this will constitute cause for the denial of employment or immediate dismissal.
Required Experience:
IC
About Company
KBI Biopharma Inc. is a global contract development and manufacturing organization (CDMO / CMO) offering Cell Line Development, Process Analytical & Formulation Development, Clinical & Commercial Manufacturing, and more.
