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Supply Chain Senior Manager


Job Location:

Boston, MA - USA

Monthly Salary: $ 133600 - 200400
Posted: 19 July 2026 (30+ days ago)
Application Deadline: 16 October 2026
Vacancies: 1 Vacancy

Job Summary

Job Description

Senior ManagerCelland Gene TherapyCommercialSupply Chain Commercial Manufacturing & Supply Chain Vertex Pharmaceuticals (Boston)

TheSenior Managerof Cell and GeneTherapyCommercial Supply Chainwilldriveslotmanagementoperationsto support Vertexsautologouscell and gene therapyprogram.Theslot managementmodelincludesdynamicshortrange andsituationalplanning and operationsto allowvisibility andpatient scheduling.TheSenior Managerwillbe responsible forestablishingmaintaining revising andexecutingslotmanagementrules and principlesto ensure patients are appropriately scheduledwithinmanufacturingcapacity and regulatory requirements.This includes chairingCDMO andcross-functionalmeetings anddrivingcontent ofkey presentations to cross-functional leaders.Through cross-functional alignment theSenior Managerwill drive thedataused in thecreationmaintenance and usageofaKey PerformanceIndicators(KPIs)Dashboard. In this role theSenior Managerwillberesponsible forcreating business processes and opportunities to ensure capacity utilization across the Supply Chain network.This includes representation as key Supply Chain lead for cross-functional workstreamsand initiatives.TheSenior Managerwill work closely withkey stakeholdersincludingtheFinanceRegulatoryCommercialLogistics Manufacturingand Vertexs Cell and Gene Therapy Site.

Key Responsibilities:

  • Lead initiatives to deliver innovative and impactful business resultsbyleveragingknowledge ofCGT Supply Chain processes.

  • Proactivelyidentify document and resolve risks through the Risk Management program.

  • Compliantly drive issues to resolution

  • Applyexpertiseof CGT Supply Chainand enable development of thatexpertisewithin the team and cross-functionally

  • Interacts with senior level management

  • Create content forexecutive level presentations on critical supply chain issues initiatives and projects.

  • Participate in creatingfunctional/department goals

  • Drive systemrequirements compliance testing andutilizationto meetthe needs of patients.

  • Support the development of potential agentic AI solutions for slot management by contributing to solution design cross-functional discussions and practical recommendations that help shape scalable and effective approaches.

  • Identifyand implement new processes and capabilities needed to supportCell and Gene Therapyprograms.

  • Anticipate future industry trendsand keep abreast withastrongfoundationof knowledge of manufacturing development and supply

Minimal Requirements:

  • Bachelors degree in a scientific or business discipline preferred or equivalent years of relevant experience

  • 6 years of Biotech Pharmaceutical or medical device company related work experience

  • Ability to analyze straightforward problems and developpossible solutionsusing technical experience and judgment; may escalate unusual or complex problems

  • Ability to effectively balance customer expectations with internal/team expectations

  • Exhibits robust knowledge across supply chain disciplines

  • Demonstrates strong aptitude for managing and motivating others and building team unity

  • Proven ability to manage multiple projects with high degree of effectiveness

  • High level understanding of GMP processes and regulatory requirements

Strong written and verbal communication skills to exchange relevant and at times complex information cross-functionally and ensuring understanding

Pay Range:

$133600 - $200400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.

At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at


Required Experience:

Senior Manager


About Company

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Vertex Pharmaceuticals invests in scientific innovation to create transformative medicines for people with serious diseases.

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