Structural Biology Research Scientist
Bethesda, MD - USA
Job Summary
Job Family:
Biologist
Travel Required:
Clearance Required:
What You Will Do:
We are seeking a Structural Biology Research Scientist to supportthe National Institute of Allergy and Infectious Diseases (NIAID)through viral protein construct design expression optimization protein purification and cryo-electron microscopy studies that advance vaccine development. Ideal candidates will bring structural virology experience and skills in assay development data analysis reporting and mentorship.This is a full-time on-site opportunity in Bethesda MD.
Responsibilities:
Design and generate expression constructs for viral proteins (e.g. envelope glycoproteins capsid proteins regulatory proteins).
Develop andoptimizeexpression systems (mammalian insect or stable cell lines).
Purify proteins using chromatography methods (affinity SEC ion exchange).
Perform binding and antigenicity assays (e.g. ELISA BLI SPR)
Conduct biochemical and biophysical characterization (e.g. SEC-MALS DLS)
Prepare samples and optimize vitrification conditions for cryo-EM studies
Operate and/or coordinate use of cryo-EM instruments (e.g. Titan Krios Glacios)
Prepare technical reports figures and manuscripts
What You Will Need:
PhD in Structural Biology or a related field
Microsoft Office
Technical experience needed to assist in studying the basic principles of plant and animal life.
Technical support and troubleshooting of sophisticated equipment.
At least 2 (two) years of experience
Must be able to obtain and maintain a Federal or DoD public trust; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred
What Would Be Nice To Have:
Previous experience supporting NIH
What We Offer:
Guidehouse offers a comprehensive total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical Rx Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement Personal Development Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care Hospital Indemnity Accident Insurance Legal Assistance and ID theft protection etc.)
Position may be eligible for a discretionary variable incentive bonus
About Guidehouse
Guidehouse is an Equal Opportunity EmployerProtected Veterans Individuals with Disabilities or any other basis protected by law ordinance or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
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Required Experience:
IC
About Company
Guidehouse is the only scaled advisory consultancy in the world to fully integrate commercial and public or government businesses within each of our industry segments because complex problems require both perspectives to address and outwit.