Sr. Scientist, Immuno-Oncology Research

The Role

Moderna is looking for a talented and motivated Senior Scientist to focus on discovery design and preclinical development of new mRNA-based immunotherapies for cancer. Successful candidates will primarily work with in vitro and ex vivo systems as well as design and analyze in vivo studies to characterize the performance of novel therapeutics. Applicants should be great team members have a demonstrable track record of independent research accomplishments and the ability to mentor junior colleagues. The ability to effectively communicate and collaborate with others as well as a passion for drug discovery are required.

Heres What Youll Do

• Collaborate with internal teams to evaluate novel mRNA therapeutics (cellular and biochemical endpoints)

• Develop characterize and validate in vitro assays and animal models to test various mRNA therapeutics

• Collect archive organize and analyze samples including those from in vivo studies and execute downstream analyses

• Deliver reproducible and impactful results under ambitious timelines

• Execute and troubleshoot standard protocols adapt new protocols into practice and query literature to incorporate additional assays as needed

• Independently plan experiments and analyze interpret and present data in program team department and cross-functional meetings

• Ideate novel or next gen therapeutic concepts using historical/platform knowledge published reports or experimental data

• Mentor or manage junior scientists to expand scientific and people impact

• Faithfully document scientific work

• Contribute to reports patent filings regulatory submissions and presentations for both in/external consumption

Heres What Youll Bring to the Table (Minimum Qualifications)

• Ph.D. in a biological science or B.S/M.S. with extensive relevant experience and at least 2 years industry experience.

• Solid background in immunology immuno-oncology and/or tumor biology

• Demonstrated ability to independently design and execute experimental plans for a preclinical drug development program

• Demonstrated ability to work in a fast-paced highly collaborative and cross-functional team environment

Heres What Youll Bring to the Table (Preferred Qualifications)

• 5 years of industry experience.

• Expertise in multi-parameter conventional and spectral flow cytometry

• Expertise phenotyping murine NHP and human immune cells

• Expertise executing primary immune cell assays and mechanism of action studies

• Experience with biodistribution pharmacokinetic and pharmacodynamic analyses using biochemical and flow cytometry assays

• Nucleic acid quantification expertise:

  • Isolation of nucleic acids from cultured cells and harvested tissue

  • Quantification via qPCR other formats such as bDNA-based approaches

• Protein quantification expertise:

  • Isolation of protein lysates from cultured cells and harvested tissue

  • Protein quantification via Western ELISA MSD Luminex-based assays

• Tissue/cell culture expertise:

  • Cell passaging archiving transfection and cell-based functional assays

  • Primary cell isolation and culture particularly with hematopoietic cells

  • Extremely sound tissue culture and general laboratory techniques

• Scientific rigor strong work ethic results orientation adaptable strong communication skills

• A desire to make an impact as part of a high-growth transformational company that is Bold Relentless Curious and Collaborative

Pay & Benefits

At Moderna we believe that when you feel your best you can do your best work. Thats why our benefits and well-being resources are designed to support youat work at home and everywhere in between.

• Competitive healthcare plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being with access to fitness mindfulness and mental health support
• Family planning benefits including fertility adoption and surrogacy support
• Generous paid time off including vacation volunteer days sabbatical global recharge days and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $130800.00 - $209400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individuals position within the salary range will be based on several factors including but not limited to specific competencies relevant education qualifications certifications experience skills performance and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus other incentive compensation or equity award subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine we invite you to visit to learn more about our current opportunities.

Our Working Model

As we build our company we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation teamwork and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.

Moderna is a smoke-free alcohol-free and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.

Accommodations

Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .

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