Sr Principal Scientist Non-Regulated Immunoassay Leader

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Lets do this. Lets change the world. Amgen is seeking an experienced and highly motivated Senior Principal Scientist Non-Regulated Immunoassay Leader to join the PKDM organization at our Thousand Oaks California site. This scientific leadership role will provide strategic operational and hands-on laboratory leadership for non-regulated immunoassay activities supporting biologics programs across a diverse therapeutic portfolio.

The successful candidate will serve as a technical leader with deep expertise in immunoassay development qualification/validation and bioanalysis across multiple assay platforms. This individual will lead laboratory activities drive scientific innovation mentor scientists and collaborate cross-functionally to deliver high-quality bioanalytical data supporting soluble target protein measurements and pharmacokinetic assessments.

This role requires a strong balance of scientific leadership operational excellence strategic thinking and hands-on laboratory engagement in a dynamic matrixed environment.

Responsibilities include:

• Lead scientific strategy and execution for non-regulated immunoassay development and bioanalysis activities supporting pharmacokinetic and soluble target protein measurements.
• Provide technical leadership across a range of immunoassay platforms including ELISA MSD/ECL Gyrolab Quanterix AlphaLISA and emerging technologies.
• Design develop optimize qualify and validate immunoassays supporting biologics research and development.
• Oversee sample analysis activities to ensure delivery of high-quality scientifically rigorous data within established timelines.
• Drive operational excellence within the laboratory including workflow management prioritization troubleshooting laboratory planning and continuous improvement initiatives.
• Serve as a scientific subject matter expert for immunoassay technologies and bioanalytical strategies.
• Collaborate closely with Discovery Research Precision Medicine Translational Safety and Risk Sciences and cross-functional program teams.
• Interpret complex scientific data and communicate results effectively to multidisciplinary stakeholders and senior leadership.
• Mentor and develop scientific staff while fostering a collaborative and innovative scientific environment.
• Evaluate and implement new technologies to expand laboratory capabilities and improve assay performance.
• Maintain accurate scientific documentation and ensure adherence to internal standards and best scientific practices.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a collaborative leader with these qualifications.

Basic Qualifications:

Doctorate degree and relevant post-doc where applicable and 3 years of scientific experience

OR

Masters degree and 6 years of scientific experience

OR

Bachelors degree and 8 years of scientific experience

Preferred Qualifications:

• PhD in Immunology Biochemistry Bioanalytical Sciences Pharmaceutical Sciences or related scientific discipline
• 510 years of relevant industry experience in immunoassay development and bioanalysis
• Demonstrated expertise in development qualification/validation and sample analysis for non-regulated immunoassays
• Strong hands-on experience across multiple immunoassay platforms and detection technologies
• Proven ability to independently lead complex scientific programs and solve technical challenges
• Experience leading laboratory operations and managing competing priorities in a matrixed environment
• Prior people management or supervisory experience preferred
• Strong understanding of bioanalytical strategies supporting biologics programs
• Excellent scientific communication presentation and technical writing skills
• Demonstrated ability to influence cross-functional teams and drive scientific strategy
• Passion for mentoring scientists and fostering technical development

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range