Sr. Lead Biostatistician Oncology Evidence Generation
Job Location:
Durham, NC - USA
Monthly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
Labcorp is a global leader in laboratory services providing the insights and answers that help healthcare providers patients researchers pharmaceutical companies and health systems make confident decisions and improve outcomes. Through our unparalleled science data technology and laboratory network we advance diagnostics accelerate innovation and help address some of the worlds most important health challenges. As we shape the future of healthcare we are leveraging advanced technologies intelligent digital solutions and data-driven innovation across our operations to enhance how work gets done and deliver greater value to customers and patients. With our global scale and deep expertise youll have the opportunity to do meaningful work grow your career and make a real impact on peoples health around the world. Together were improving health and improving lives.
Labcorp is seeking a SeniorLead Biostatistician Oncology Evidence Generationto join our team in Raleigh/Durham NC.
Work Schedule: Monday - Friday First Shift
Job Summary:
Labcorp is seeking a Senior Lead Biostatistician to join our cross-functional Evidence Generation team supporting a growing portfolio of oncology research initiatives with a focus on observational clinical validity studies in minimal residual disease (MRD) alongside investigator-initiated studies registries and real-world evidence programs. This role will serve as the statistical lead across multiple studies driving study design analytical strategy and execution to ensure high-quality scientifically rigorous outputs.
The Senior Lead Biostatistician will act as a central statistical leader partnering closely with clinical development scientific data and operational teams as well as external investigators and collaborators. This individual will ensure studies are appropriately designed powered and analyzed while delivering high-quality statistical outputs that support evidence generation publication and clinical adoption. The role plays a critical part in translating complex data into meaningful insights and advancing Labcorps precision oncology evidence strategy.
Job Responsibilities:
- Contribute to and shape the design of MRD-focused studiesincluding clinical validity studies registries and real-world evidence programs defining endpoints analysis strategies and overall statistical approach across multiple concurrent programs
- Perform sample size and power calculations support endpoint justification and draft statistical sections of study protocols
- Independently perform statistical analyses across diverse datasets (clinical assay/validation and real-world/registry data) using appropriate methods (e.g. regression survival analysis validation approaches) ensuring accuracy reproducibility and appropriate documentation
- Serve as the statistical point of contact for assigned studies; partner with clinical translational and data teams as well as external collaborators to support study execution and communicate statistical concepts methods and results clearly to non-statistical stakeholders
- Identify study risks and provide data-driven recommendations to support study integrity and decision-making
- Develop manage and maintain statistical deliverables (analysis summaries tables/listings/figures study reports) and lead or contribute to the development of Statistical Analysis Plans (SAPs)
- Contribute to abstracts manuscripts and scientific presentations supporting evidence generation and publication strategy
- Manage statistical deliverables across multiple concurrent studies ensuring timelines quality and consistency of outputs
- Lead or contribute to development of statistical templates tools and workflows while building subject matter expertise in MRD and oncology study methodologies
Minimum Requirements:
- MSin Biostatistics Statistics or a related quantitative field
- 6or moreyears of experience in clinical biostatistics within biotechnology diagnostics CRO or related healthcare environments
- 5or more yearsof experiencein statistical programming (R SAS or equivalent acceptable)
- 3 or more years ofexperience supporting clinical research studies including observational studies registries and/or assay validation efforts
- 3 or more years of experienceindependently managingstatistical analyses and deliverables across multiple concurrent studies
Preferred Requirements:
- PhD in Biostatistics Statistics or a related quantitative field
- 3 or more years of experience in oncology research biomarker-driven studies or precision oncology
- 3 or more years of experience with real-world data registry-based research or observational study designs
- 3 or more years of experience contributing to scientific publications including abstracts manuscripts or conference presentations
- 1 or more years of experience with MRD ctDNA genomics/NGS-based assays or molecular diagnostics
- 1 or more years of experience with clinical study documentation and regulatory standards (e.g. protocols SAPs GCP principles)
Additional Job Standards:
- Strong foundation in clinical study design and applied statistical leadership including sample size estimation power calculations and endpoint evaluation
- Experience applying statistical methods to clinical real-world and/or assay validation datasets including regression and survival/time-to-event analysis
- Strong written and verbal communication skills with ability to clearly convey complex statistical concepts to diverse scientific and non-technical audiences
- Demonstrated ability to work effectively in cross-functional teams and collaborate with internal stakeholders and external partners
- Strong analytical problem-solving and organizational skills with high attention to detail and commitment to data quality and scientific rigor
- Experience working in collaborative research environments involving academic or external investigator partnerships
- Occasional travel for internal meetings or external collaborator engagement as needed (1015%)
Benefits:Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical Dental Vision Life STD/LTD 401(k) Paid Time Off (PTO) or Flexible Time Off (FTO) Tuition Reimbursement and Employee Stock Purchase regularly scheduled to work less than 20 hours Casual Intern and Temporary employees are only eligible to participate in the 401(k) more detailed information pleaseclick here.
Labcorp is proud to be an Equal Opportunity Employer:
Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race religion color national origin sex (including pregnancy childbirth or related medical conditions) family or parental status marital civil union or domestic partnership status sexual orientation gender identity gender expression personal appearance age veteran status disability genetic information or any other legally protected characteristic. Additionally all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.
We encourage all to apply
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Required Experience:
Senior IC
About Company
Labcorp helps patients, providers, organizations, and biopharma companies to guide vital healthcare decisions each and every day.
