Sr Director, US Medical Early Assets Market Access

SrDirector US Medical Early Assets - Market Access

Are you ready to turn ideas into life-changing medicines At AstraZeneca we are committed to addressing the unmet needs of patients worldwide through scientific innovation. Reporting directly to the Executive Director US Medical Early Asset Team Lead you will be part of a team focused on the development of ambitious US medical strategies for our early pipeline. Youwillinfluence across a complexglobalmatrixto ensure USpayer health-system policy and affordabilityneeds are integrated intoassetdevelopmentand investment decisions.

Accountabilities:

The Sr Director US Medical Early Asset - Market Access is the strategic lead for shaping the US access and value strategy for our BBU portfolio pipeline assets from late discovery through Phase 2. The Senior Director ensures that payer health-system policy pricing and affordability considerations are incorporated early into asset development evidence generation and investment decisions. Serving as the senior US access voice on cross-functional asset teams the Senior Director provides clear evidence-based recommendations that strengthen future differentiation reimbursement and patient access.

Key Responsibilities

• US Value Strategy and TPP Input: Define US payer-relevant elements of theTarget Product Profile(clinical endpoints comparators subpopulations line of therapy) and shape differentiation claims that resonate with payers and health systems.

• Evidence and Study Design Influence: Provide US access input to clinical and RWE plans (endpoints PROs inclusion/exclusion duration head-to-heads external controls) to support label compendia guideline inclusion and payer coverage.

• Payer Value Proposition & Dossier Foundations: Lead early value story development (unmet need clinical and economic value drivers) outline core claims and define requirements for future AMCP dossier modules and global value dossiers.

• Early Pricing and Contracting Hypotheses: Develop US WAC/NET ranges reference pricing considerations budget impact boundaries and contracting scenarios (e.g. outcomes-based indication-based) with assumptions and risks.

• HEOR & RWE Strategy: Co-create early economic models and RWE plans (burden of illness treatment patterns comparative effectiveness adherence/persistence) to support access and inform trial design.

• Access Policy and Channel Strategy: Assess policy landscape (Medicare Medicaid ACA IRA/Part D redesign 340B state policies) site-of-care and channel dynamics (buy-and-bill pharmacy benefit specialty distribution) and implications for design and launch.

• Payer IDN and PBM Insights: Plan and synthesize early payer/IDN advisory input and rapid tests (concept reviews value message testing coverage criteria simulations) to de-risk access hurdles.

• Competitive and Class Access Analytics:Maintainlandscape of class coverage criteria step/edit rulesutilizationmanagement coding/reimbursement precedents;identifyopportunities to differentiate andanticipatebarriers.

• Forecasting & Investment Support: Build access assumptions for early forecasts (gross-to-net access mix UM intensity speed-to-coverage) and partner with Finance onrNPV/scenario analyses for governance.

• Governance and Cross-Functional Leadership: Represent US access in global/US asset teams and at governance gates (indicationsequencing go/no-go TPP approval) driving clear evidence-backed recommendations.

• Compliance and Ethics:Operatewithin US promotional and pre-approval communication standards and company policies; ensure research and external interactions meet compliance requirements.

MinimumQualifications

• Bachelors degreein health economics public health pharmacy life sciences business economics or a related discipline;advanceddegreesuchasanMPH MSPharmDPhDorMBA strongly preferred.
• 8yearsof progressive experienceinthe pharmaceutical biotechnology healthcare payerorconsultingenvironmentincludingsubstantialexperience inUSMarketAccessHEORpricing and reimbursement orearlyassetstrategy.
• Profilesclinicaldevelopmentplansevidencestrategiesandassetinvestmentdecisions.
• DeepunderstandingoftheUSpayerandhealthsystemenvironmentincludingcommercialandgovernmentpayersmedicalandpharmacybenefit dynamics pricing and reimbursementutilizationmanagement distribution and site-of-care considerations and relevant policy trends.
• StrongunderstandingofHEORrealworldevidencepayerresearcheconomicmodelingandvalueproposition development with the ability to translate technical analyses into strategic recommendations.
• Demonstratedexperiencerepresentingafunctionormarketperspectiveoncross-functionalasset teams governance forums or senior decision-making bodies.
• Proven ability toinfluence senior stakeholders andleadacrossClinical DevelopmentMedical HEORRegulatoryCommercialFinance Policyandglobal market access organizations without direct authority.
• Strongstrategicjudgmentand the abilitytomakeclearrecommendations in conditions of scientific commercialandaccessuncertainty.
• Execellent communicationskillsincludingthe ability to synthesize complex information construct a compelling valuenarrativeandinfluenceseniorandglobalstakeholders.
• Demonstratedabilitytomanagemultiple assetsprioritiesanddecisiontimelinesina complex matrixed environment.

Preferred Qualifications

• Advanced degree in health economics outcomes research public health pharmacy medicine science economics or business.
• Experience spanning more than one relevant discipline such as Market Access HEOR Clinical Development Medical Affairs new product planning pricing policy or finance.
• Direct experience supporting early-stage or first-in-class assets from late discovery through Phase 2.
• Experience influencing global asset strategy and translating US access needs into global development and evidence plans.
• Experience contributing to governance decisions involving asset progressionindicationprioritizationevidenceinvestment licensing or portfolio prioritization.
• Experience developing innovative pricing contracting or value-based access approaches.
• Therapeutic-areaexperience relevant to the assigned pipeline portfolio.
• Experience coaching colleagues or building organizational capability in early market access HEOR payer strategy or value development.

This position is based at our Wilmington DE campus headquarters for our US Biopharma we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Next Steps Apply Today!

Are you ready to make a difference Apply now and join our mission to transform lives with our science!

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Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.