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Sr. Director Product Portfolio Management

McKesson


Job Location:

Irving, TX - USA

Monthly Salary: $ 172500 - 287500
Posted: 10 June 2026 (30+ days ago)
Application Deadline: 7 September 2026
Vacancies: 1 Vacancy

Job Summary

McKesson is an impact-driven Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights products and services that make quality care more accessible and affordable. Here we focus on the health happiness and well-being of you and those we serve we care.

What you do at McKesson matters. We foster a culture where you can grow make an impact and are empowered to bring new ideas. Together we thrive as we shape the future of health for patients our communities and our people. If you want to be part of tomorrows health today we want to hear from you.

The Product Portfolio Management Leader for Generics Programs & Products shapes a product-focused portfolio strategy and translates market and customer insights into forward-looking lifecycle decisions for existing products and new product launches. Working in close partnership with stakeholders across the enterprise this leader ensures portfolio actions align with Generics and enterprise priorities and drive long-term value.

Reporting to the VP Generics Programs & Products this role leads the Product Portfolio Management organization through a Sr. Manager of Campaigns and a Category Management function. The team brings deep therapeutic expertise portfolio-optimization capabilities training development and robust product P&L management to identify and execute portfolio-maximization opportunities across current products and new product launches.

The leader partners extensively across a highly matrixed organization including Segment Leaders; Reporting; Insights & Analytics; Pricing Insights & Intelligence; and market-facing teams. Upstream the role works with ClarusONE Masters NorthStar and BSMR to evaluate align and consult on profitable scalable portfolio decisions that drive enterprise growth. Success requires strong financial and business acumen clear portfolio vision and exceptional communication and influencing skills.

As a strategic member of the leadership team this role is also responsible for establishing and strengthening core product portfolio management capabilities that enable effective execution of the Generics product strategy across all segments.

Key Responsibilities

  • Lead the Product Portfolio Management team in developing and advancing a multi-year end-to-end product and portfolio strategy and launch timeline across all segments aligned to the Generics roadmap and enterprise priorities.

  • Drive portfolio planning and prioritization shape product mix and pricing posture and align strategic customer focus areas while escalating high-impact financial insights to ensure sustained enterprise value and long-term growth.

  • Deliver team outcomes through defined SLAs and success metrics.

  • Represent Generics Programs & Products in leadership forums and partner with senior and executive stakeholders (e.g. Segment Leaders; Reporting; Insights & Analytics; Pricing Insights & Intelligence; and market-facing teams) to shape and influence portfolio decisions.

  • Lead and develop a team of direct reports (including a Sr. Manager and Category Management function) in a fast-paced Generics Programs & Products environment; provide mentorship coaching and career development while adapting to evolving business needs.

  • Communicate the Generics Programs & Products vision and translate it into a functional strategy for the Product Portfolio Management team.

  • Translate customer needs market insights competitive intelligence and field feedback into actionable product requirements and strategic roadmaps.

  • Oversee the full product lifecyclefrom concept and incubation through launch scale and end-of-lifeensuring cohesive execution and enterprise alignment.

  • Partner with key stakeholders (including Reporting Insights & Analytics and FP&A) to validate roadmap feasibility leverage insights for data-driven decisions and budget forecast and track financial performance (e.g. NPL).

  • Guide development of executive communications messaging and insights for each BU/segment related to product and portfolio performance (e.g. sales compliance trends savings opportunities and risks).

  • Guide development of conversion playbooks (including identifying NPL conversion opportunities training strategy and customer knowledge) to maximize launch performance and lifecycle optimization improve margins and drive financial growth.

Minimum Requirement

Degree or equivalent experience. Typically requires 13 years of professional experience and 6 years of diversified leadership planning communication organization and people motivation skills (or equivalent experience).

Education

  • Bachelors degree required (Business Engineering Marketing or related field preferred)

  • MBA or advanced degree in Business Finance Product Strategy or related is strongly preferred

Critical Skills

  • 13 years of relevant experience including systems and product portfolio management (existing products and NPL) financial and P&L management; plus 6 years of diversified business and people leadership (or equivalent experience). Fortune 100 experience preferred.

  • Industry experience in healthcare pharmaceutical life sciences or large-scale B2B pricing environments is a plus

Additional Knowledge & Skills

  • Deep enterprise-level expertise in Product Management related to Generic Product substitution pricing and contract hierarchy; experience owning and governing complex existing and NPL portfolios across the full product lifecycle and roadmap

  • Demonstrated ability to shape and execute existing and new product portfolio strategy that delivers sustained enterprise and customer value and supports longterm generics growth objectives

  • Experience with applying AI-driven analytics and decision-support tools that help shape and optimize the product portfolio strategy and make informed roadmap decisions for existing and new product launches

  • Deep enterprise-level expertise in Generics systems policies practices and Finance with superior business and financial acumen

  • Enterprise pricing leadership experience including governance of complex programs pricing frameworks and contract structures

  • Proven success leading complex customer negotiations with the ability to interpret apply and execute against sophisticated pricing and program models

  • Enterprise leadership presence with the ability to influence without authority defend strategic positions and lead effectively within a highly matrixed organization across multiple functions

  • Ability to align and mobilize senior leaders and cross-functional stakeholders gaining commitment and driving shared ownership of outcomes

  • Executive-level communication and storytelling capability with proven experience translating complex concepts insights and recommendations into clear compelling narratives for senior leadership

  • Strong track record of driving results through others including setting direction prioritizing enterprise initiatives and ensuring execution accountability and follow-through

  • Recognized as a creative strategic problem solver challenging conventional approaches and driving innovative solutions that advance enterprise objectives

Working Conditions

Environment (Office warehouse etc.)

  • Standard Office work

Physical Requirements (Lifting standing etc.)

  • Standard Office Work

Travel

Up to 20% (as business needs require)

This role is a hybrid position. The selected candidate is expected to work on-site at our Las Colinas office a minimum of two (2) days per week with the remaining days worked remotely. Specific in-office days may be designated based on team needs and business priorities.

McKesson complies with all applicable U.S. immigration laws and regulations. The Company does not provide employer support or sponsorship for any immigration related employment benefit for this role.

Applicants must be currently authorized to work in the United States on a fulltime basis without the need for employer support or sponsorship now or in the future. This includes having the legal right to work in the United States without the need for McKesson support or sponsorship for any immigration related employment authorization (e.g. H1B O1 E3 H1B1 TN F1 OPT F1 STEM OPT F1 CPT etc.) now or in the future.

If you will require McKesson to provide immigration support or sponsorship now or in the future you should not apply for this position

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors including performance experience and skills equity regular job market evaluations and geographical markets. The pay range shown below is aligned with McKessons pay philosophy and pay will always be compliant with any applicable regulations. In addition to base pay other compensation such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson pleaseclick here.

Our Base Pay Range for this position

$172500 - $287500

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKessons (or affiliated entities like CoverMyMeds or RxCrossroads) name in fraudulent emails job postings or social media light of these scams please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: .

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability age genetic information or any other legally protected category. For additional information on McKessons full Equal Employment Opportunity policies visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment please contact us by sending an email to (United States) or (Canada) . Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!


Required Experience:

Exec


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McKesson is the leading healthcare company for wholesale medical supplies & equipment, pharmaceutical distribution, and healthcare technology solutions. McKesson is the central nervous system of health care. At any given moment, in any given minute, we simultaneously execute thousands ... View more

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