Sr. AI-First Full Stack Engineer

McKesson is an impact-driven Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights products and services that make quality care more accessible and affordable. Here we focus on the health happiness and well-being of you and those we serve we care.

What you do at McKesson matters. We foster a culture where you can grow make an impact and are empowered to bring new ideas. Together we thrive as we shape the future of health for patients our communities and our people. If you want to be part of tomorrows health today we want to hear from you.

McKesson is seeking a Senior AI-First Full Stack Engineer to build the next generation of intelligent healthcare technology solutions supporting one of the nations leading and fastest-growing specialty pharmacy organizations. This role combines strong full stack engineering with Generative AI innovation to deliver production-grade applications powered by modern web technologies REST APIs cloud-native platforms enterprise data and integrations Large Language Models (LLMs) and AI agents in a fast-paced healthcare environment where technology directly impacts patient provider and business outcomes.

The engineer will work across the entire software lifecycle from business discovery system design and full stack application development through testing cloud deployment production support and measurable adoption. The role requires a hands-on builder with strong front-end back-end API data integration and cloud engineering fundamentals who can apply AI as an additional capability and engineering accelerator. The engineer must translate ambiguous business problems into practical solutions collaborate directly with stakeholders and establish standards for secure reliable and scalable delivery across specialty pharmacy patient engagement provider solutions and operational platforms.

Our team supports fast-paced specialty pharmacy operations patient engagement provider services and business-critical healthcare workflows where speed reliability scalability and innovation directly contribute to patient outcomes and business growth. Success in this role comes from partnering closely with the business to rapidly validate solutions transform prototypes into scalable production capabilities and maintain accountability for adoption reliability and outcomes.

• Design develop and deploy AI-powered applications using Claude (Anthropic) Azure OpenAI OpenAI and Azure AI Services.
• Partner directly with business stakeholders to define problems validate workflows rapidly prototype solutions and convert successful concepts into production capabilities.
• Build RAG solutions prompt frameworks AI workflows and autonomous or agentic systems with human-in-the-loop controls.
• Develop full stack applications using React TypeScript Python C# Java .
• Design REST APIs microservices event-driven architectures and enterprise integration patterns.
• Integrate AI capabilities with ServiceNow Salesforce Snowflake Databricks Power BI and other enterprise platforms.
• Develop cloud-native solutions on Microsoft Azure using secure engineering and DevOps practices.
• Build CI/CD pipelines Infrastructure as Code containerized workloads and Kubernetes deployments.
• Serve as technical owner for assigned applications or platforms establishing architecture standards engineering guardrails SLOs and production-readiness criteria.
• Lead modernization technical debt reduction resiliency improvements design reviews incident resolution and root-cause prevention.
• Mentor engineers and influence architecture security data product and delivery decisions across teams.

• 7 years of professional software engineering experience developing enterprise-scale applications.
• Bachelors degree in Computer Science Engineering Information Technology or a related field or equivalent practical experience.
• Hands-on experience building and deploying applications using Java C# Python or comparable backend technologies.
• Experience developing modern front-end applications using React and TypeScript.
• Experience designing and consuming REST APIs microservices and enterprise integrations.
• Experience developing cloud-native applications on Microsoft Azure.
• Experience with CI/CD source control automated testing SDLC and Agile practices.
• Experience acting as a technical lead or primary owner for an enterprise application service or platform.
• Experience designing scalable architectures documenting trade-offs and supporting production systems.
• Demonstrated ability to turn ambiguous business needs into delivered technical solutions.

• Experience with Azure AI Services Azure OpenAI Azure AI Foundry Cognitive Services and enterprise AI platforms.
• Experience building Generative AI solutions using Azure OpenAI OpenAI Claude or comparable LLM platforms.
• Strong programming experience with Python C# TypeScript JavaScript Java technologies.
• Experience developing full stack applications using React TypeScript Python and C#/.NET.
• Experience designing developing securing and supporting REST APIs and enterprise integration services.
• Experience with Databricks Snowflake and governed enterprise data and analytics platforms.
• Experience with RAG semantic search vector databases AI orchestration agentic AI guardrails evaluation and human-in-the-loop workflows.
• Experience with Salesforce platform development integrations REST APIs workflows and data services.
• Experience integrating with or supporting ServiceNow workflows ITSM CMDB service catalog and automation processes.
• Experience developing data visualization analytics and operational reporting solutions using Power BI.
• Experience with Docker Kubernetes Infrastructure as Code Azure Monitor Application Insights or comparable platforms.
• Knowledge of distributed systems event-driven architecture asynchronous processing and resiliency patterns.
• Experience leading application modernization cloud transformation or platform engineering initiatives.
• Experience in healthcare specialty pharmacy regulated industries or high-compliance environments.

• Hybrid or remote work arrangement based on business needs.
• Limited travel may be required for collaboration planning stakeholder discovery or solution workshops.
• Ability to work on a computer for extended periods and participate in virtual collaboration activities.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors including performance experience and skills equity regular job market evaluations and geographical markets. The pay range shown below is aligned with McKessons pay philosophy and pay will always be compliant with any applicable regulations. In addition to base pay other compensation such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson pleaseclick here.

Our Base Pay Range for this position

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKessons (or affiliated entities like CoverMyMeds or RxCrossroads) name in fraudulent emails job postings or social media light of these scams please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: .

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability age genetic information or any other legally protected category. For additional information on McKessons full Equal Employment Opportunity policies visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment please contact us by sending an email to (United States) or (Canada) . Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!