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Senior Supply Chain Manager
Job Location:
Job Location:
Waltham, MA - USA
Monthly Salary:
$ 135000 - 165000
Monthly Salary:
Posted:
12 August 2026 (6 hours ago)
Posted:
Application Deadline:
9 November 2026
Application Deadline:
Vacancies:
1 Vacancy
Vacancies:
Department:
Job Summary
Description
Ardelyx is a commercial-stage biopharmaceutical company focused on redefining treatment approaches for patients with significant unmet medical needs. By combining scientific innovation with a collaborative purpose-driven culture we strive to create meaningful impact for patients.
Team Ardelyx is united by a shared mission and guided by our core values: Passionate Fearless Dedicated and Inclusive.
We foster an inclusive environment where employees are respected supported and empowered to make an impact both within our company and in the lives of patients we serve.
Team Ardelyx is united by a shared mission and guided by our core values: Passionate Fearless Dedicated and Inclusive.
We foster an inclusive environment where employees are respected supported and empowered to make an impact both within our company and in the lives of patients we serve.
This is a hybrid role (2-3 days in office) at our Waltham MA headquarters.
Position Summary:
This role is responsible for leading and supporting Ardelyxs API external manufacturing inventory management and contract manufacturing organization (CMO) partners. The Senior Supply Chain Manager provides oversight of CMO partners to ensure the timely delivery of materials effective cost management supply continuity and execution of change controls.
Working closely with Supply Chain team Technical Operations Quality CMOs and other cross-functional partners this role supports API production activities across the supply network. Key responsibilities include monitoring inventory accuracy resolving supply chain issues coordinating logistics activities ensuring compliance with ex-US market requirements and driving continuous improvement initiatives across the API supply network.
The ideal candidate brings strong pharmaceutical supply chain experience exceptional organizational and project management skills and the ability to manage multiple priorities in a fast-paced cross-functional environment.
Responsibilities:
- Partner with third-party manufacturers to align production schedules raw materials quality requirements and regulatory compliance for small molecule APIs
- Manage Ardelyx inventory across API-related CMO sites ensuring accurate inventory control and efficient supply chain operations
- Manage purchase requisitions and purchase orders related to small-molecule API manufacturing and material movements. Monitor expenses against approved budgets and support accrual processes with Finance and Accounting
- Work cross-functionally with Quality Assurance CMC and Regulatory Affairs to support supply planning activities identify potential risks and develop proactive mitigation plans
- Use ERP systems and planning tools to model scenarios track supply risks and optimize logistics. Maintain supply chain policies procedures and documentation and support training activities as needed
- Prepare reports metrics and presentations for management and cross-functional stakeholders
- Complete API and RSM related change control impact assessments
- Work with Supply Chain Director to ensure ex-US alliance orders are delivered timely and in accordance with contractual obligations and requirements
Qualifications:
- BA/BS in a technical scientific engineering supply chain or related discipline with 6 -8 years of experience in pharmaceutical supply chain or CMC project management.
- Demonstrated experience in API project management or supply chain for a virtual supply chain network
- Experienced in managing external manufacturing relationships
- Strong interpersonal skills and the ability to collaborate effectively with cross-functional teams and external partners
- Detail oriented with strong analytical and computer skills
- Excellent negotiating and problem-solving abilities
- Strong oral and written communication skills
- Demonstrated ability to organize and prioritize multiple tasks manage competing and meet deadlines in a fast-paced environment
- Up to 15% travel required
The anticipated annualized base pay range for this full-time position is $135000 - $165000. Ardelyx utilizes industry data to ensure that our compensation is competitive and aligned with our industry peers. Actual base pay will be determined based on a variety of factors including years of relevant experience training qualifications and internal equity. The compensation package may also include an annual bonus target and equity awards subject to eligibility and other requirements.
Ardelyx also offers a robust benefits package to employees including a 401(k) plan with generous employer match 12 weeks of paid parental leave up to 12 weeks of living organ and bone marrow leave equity incentive plans health plans (medical prescription drug dental and vision)life insurance and disability flexible time off annual Winter Holiday shut down and at least 11 paid holidays.
Ardelyx is an equal opportunity employer.
We do not accept unsolicited resumes from search firms or recruiters or similar vendors. Any such unsolicited resume submitted to any employee or through Companys career site without a valid signed search agreement signed by Companys authorized representative will be deemed the property of the company and no fees will be paid in the event of a hire. Company will have the right to hire any such candidate at its discretion without any financial obligation or fee owed to the vendor. Any verbal or written communication with a Company employee outside of this process will not be considered a binding agreement.
Required Experience:
Manager
About Company
From discovery through commercialisation, all of us at Ardelyx are driven to advance targeted therapies where significant medical needs persist.
