Senior Specialist, Quantitative Pharmacology and Pharmacometrics – Immuno-Oncology (QP2IO)

Job Description

Our company is a global healthcare leader with a diversified portfolio of prescription medicines vaccines and animal health products. We are recognized as an industry leader in immuno-oncology (IO) and vaccines discovery and development. For more than a century our company has translated scientific innovation into medicines and vaccines that improve and save lives worldwideanchored in ethical integrity scientific excellence and a clear mission to transform global health.

Our company is on a quest for cures and is committed to being the worlds premier most research-intensive biopharmaceutical company. Our Research & Development division is a world-class scientific organization that brings together leading discovery capabilities and small molecule/biologics R&D expertise to create breakthrough science and redefine how we treat serious diseases.

Role Overview

The Quantitative Pharmacology and Pharmacometrics Immune/Oncology (QP2-IO) Department of our Companys Research Laboratories is seeking a curious and collaborative Senior Scientist to support our rapidly expanding oncology pipelines.

As a senior specialist you will be part of a cross-functional teams of experienced scientists to discover and develop novel therapeutic agents in oncology. The senior specialist is a skilled quantitative scientist with a good understanding of the strategic elements of drug discovery and development. The senior specialist should demonstrate collaborative work spirit and excellent communication skills.

Within QP2-IO you have a unique opportunity to accelerate your professional career as a quantitative drug developer taking advantage of our end-to-end pipeline support in one of the worlds most research-intensive biopharmaceutical companies.

Primary Responsibilities:

Contribute to the development of model-based strategies (translational PK/PD strategies mechanistic model POPPK/PD clinical trial simulationsetc) for quantitative analyses within and across development programs and/or departments to inform and optimize drug discovery and all phases of drug development including but not limited to dose selection clinical trial design and go/no-go decisions.

Represent QP2-IO on oncology discovery early clinical development and late clinical development teams leveraging quantitative approaches to drive streamlined development of programs within our growing portfolio.

Collaborate with other functional areas as well as with external vendors and partners on activities related to study design protocol development study execution reporting and interpretation of data.

• Ph.D. in biopharmaceutics pharmaceutical sciences pharmacometrics mathematics systems biology microbiology immunology chemical/biomedical engineering or a related field with 0-2 years experience

OR

• PharmD or MS in biopharmaceutics pharmaceutical sciences pharmacometrics mathematics systems biology microbiology immunology chemical/biomedical engineering or a related field or equivalent degree with preferably 2-4 years of relevant experience where experience means having a record of increasing responsibility and independence in a similar role in pharmaceutical drug development regulatory agency or academia.

• Experience in performing population PK PK/PD analyses using standard pharmacometrics software (e.g. NONMEM Monolix Phoenix etc.).

• Good written and verbal communication interdisciplinary collaboration and problem scoping and planning.

• Knowledge in oncology clinical drug development programs.

• Skills in experimental design mathematical problem solving critical data analysis/interpretation and statistics.

• Scientific understanding of biopharmaceutical and ADME properties of small molecules and/or biologics.

his opportunity will be hybrid or remote but the remote position is only applicable for those that are not within commutable distance to primary sites noted in posting. If commutable the position will be hybrid. Please note that standard commute is (less than) <50 miles.

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The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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