Senior Scientist, Process Chemistry

• Design planning and execution of multi-step experimental studies to provide safe efficient robust and scalable processes.
• Independently use PAT and analytical tools and interpret data to gain reaction understanding.
• Share literature and available resources to support relevant precedent for process research.
• Perform experiments and interpret data (calorimetry TGA DSC) to safely scale reactions.
• Author development reports and technical packages and author/review relevant sections in health authority filings (including INDs NDAs annual reports and any other regulatory interactions) and patents.
• Prepare presentation materials and clearly communicate research results to manager and at internal/external meetings.
• Working cross-functionally with Analytical and Formulations Development colleagues.

Tech transfer to CMO and scale-up of chemistry including supporting GMP manufacture.

Qualifications :

• PhD in organic chemistry with at least 3 years for Senior Scientist and with 0-2 years experience for a scientist of relevant hands-on pharmaceutical/biotech industry experience in the field of new drug development.
• Proven track record for solving process chemistry problems including identification optimization and characterization of robust and scalable synthetic routes.
• Firm understanding of mechanistic organic chemistry.
• Working understanding of analytical tools used in process development (DSC TGA DVS HPLC NMR KF PLM XRPD).
• Able to work as part of a team with strong interpersonal skills. Excellent oral and written communication skills. Succinct but thorough communication skills with attention to detail analytical/critical thinking and data organization presentation and inference.
• Demonstrated passion curiosity and enthusiasm in pursuing ideas and solutions despite challenges.
• Demonstrated initiative ownership problem identification problem solving and strategic thinking.
• Experience writing research reports and detailed reaction procedures.
• Demonstrated ability to work independently and efficiently in a collaborative fast-paced integrated multidisciplinary team.
• Consistent demonstrated high performance above and beyond the minimum expectations and needs.
• Scientific excellence is demonstrated by publications presentations and leadership/engagement in the scientific/professional community.
• Awareness and understanding of ICH GMP and regulatory guidance that are important to consider in new drug development.
• Excellent oral and written communication skills. Succinct but thorough communication skills with attention to detail analytical/critical thinking and data organization presentation and inference.

Excellent oral and written communication skills. Succinct but thorough communication skills with attention to detail analytical/critical thinking and data organization presentation and inference.

Additional Information :

The anticipated salary range for candidates is between $175000-$200000 in South San Francisco.  The final rate offered to a successful candidate will be dependent on several factors that may include but are not limited to the title type and length of experience within the job type and length of experience within the industry education etc. 

ORIC Pharmaceuticals Inc. is an equal opportunity employer. ORIC does not discriminate based on race color religion gender sexual orientation gender identity age national origin disability status protected veteran status or any other legally protected characteristic.  

Remote Work :

No

Employment Type :

Full-time