Senior Scientist, Clinical Research

Job Description

The Early Clinical Scientist (ECS) coordinates the design planning and execution of early phase clinical trials with the Clinical Director and internal/external team members. Oversees trials within and/or across program(s)/therapeutic areas and ensures excellence in execution/compliance to support study objectives and data validity. Manages internal/external team performance to achieve project objectives and resolves project performance issues if they arise.

Ensures appropriate clinical safety assessment and risk management of compounds. Conducts real-time oversight of ongoing trials to identify and mitigate patient study design data or study conduct issues. Reviews and interprets clinical trial conduct on-site study monitoring including site training & supervision of complex novel endpoint/biomarker collection processes. Applies thorough knowledge of GCP ICH guidelines and regulatory requirements for clinical development.

Represents Early Stage Development on cross-functional teams to develop and/or improve internal job aids/SOP/clinical development procedures. Identifies and communicates best practices within the organization. Promotes departmental adaptation of new procedures.

Technical Writing & Communications

Co-authors clinical sections of protocols clinical investigator brochures clinical study reports Worldwide Marketing Application/Common Technical Document (WMA/CTD) subsections and regulatory agency update and safety reports as well as clinical development plans publications and abstracts. Ensures documents are completed in accordance with applicable standards. Develops study operational documents with input from team members (e.g. site monitoring plan study operations manual informed consent etc.).

Project Management

Manages trial and program projects including team activities (i.e. meetings document/collaborative workspace management etc.) provides risk assessment and contingency planning under accelerated timelines. Familiar with early drug development processes building knowledge and skills to effectively manage additional processes/procedures.

Education Minimum Requirement:

• Degree in Life Sciences

• Bachelors degree and 6 years related* experience OR

• Masters degree and 4 years related* experience OR

• PhD or doctorate with 2 years related* experience

*e.g. knowledge of clinical trial management and trial execution; clinical site training/monitoring; medical and regulatory writing

Required Experience and Skills:

• At least 3 years experience in an operational clinical scientist or study manager role in clinical research at a pharmaceutical or biotech company.

• Understanding of clinical research development process from program planning to regulatory submission

• Able to quickly develop a working scientific knowledge of different therapeutic areas

• Ability to manage complex operations and projects under accelerated timelines

• Scientific medical and/or safety writing and reporting (at least one is required)

• Ability to partner effectively with internal and external teams to achieve results

• Strong team collaboration leadership communication (written & verbal) issue identification and resolution skills

• Knowledge of GCP ICH guidelines and regulatory requirements

Preferred Experience and Skills:

• Global Phase I subject and patient trials safety reporting and regulatory WMA submission experience a plus.

• Experience managing Immunology and/or vaccine trials with an ability to think outside of the box explore novel ways of working and comfortably navigate ambiguity to drive results also a plus.

Required Skills:

Adaptability Adaptability Biopharmaceutical Industry Clinical Development Clinical Research Clinical Study Management Clinical Trial Planning Clinical Trials Clinical Trials Analysis Drug Development Ethical Compliance Ethical Standards ICH GCP Guidelines Immunology Medical Writing Multiple Therapeutic Areas Phase I Studies Project Management Protocol Development Regulatory Requirements Regulatory Submissions Regulatory Writing Risk Assessments Scientific Publications Technical Writing 1 more

Preferred Skills:

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The salary range for this role is

$117000.00 - $184200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

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Merck & Co. Inc. Rahway NJ USA also known as Merck Sharp & Dohme LLC Rahway NJ USA does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place introductions are position specific. Please no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

09/3/2026

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.