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Senior Principal Scientist, Outcomes Research

MSD


Job Location:

Boston, MA - USA

Monthly Salary: $ 210400 - 331100
Posted: 10 June 2026 (30+ days ago)
Application Deadline: 7 September 2026
Vacancies: 1 Vacancy

Job Summary

Job Description

In BARDS (Biostatistics and Research Decision Sciences) a distinguished department within our companys renowned Research and Development division quantitative scientists in partnership with other subject matter experts apply state-of-the art scientific methodologies and tools to enable the discovery development regulatory approval manufacturing and marketing of medical drugs and vaccines for the benefit of patients and global human health.

The Senior Principal Scientist leads a team of health economists to develop and implement health economics and modeling strategies that enable the Company to understand and communicate the full economic value of the Companys oncology products to payers health technology agencies policy makers and other decision-makers in order to optimize market access and patient outcomes.

Main Responsibilities:

Under the direction of an Executive Director within the Health Economic and Decision Sciences (HEDS) department of the BARDS) organization the Senior Principal Scientist will:

  • Lead a team in the development and execution of health economic and modeling strategies to support the value of the Companys oncology portfolio

  • Provide leadership mentorship and strategic direction to a team of 34 health economists

  • Oversee the prioritization and development of high-quality global health economic models and tools to support market access pricing reimbursement HTA submissions and formulary decision-making across U.S. and international markets

  • Collaborate with key countries and the regional team to adapt global models for local HTA reimbursement and formulary submissions

  • Generate and communicate early health economic insights to inform development and commercialization strategies

  • Build strong partnerships with internal stakeholders to ensure modeling strategies align and support the overall product development and value evidence strategy and implementation

  • Develop and maintain relationships with external thought leaders in health economics decision sciences and health policy to enhance scientific credibility inform strategy and position our company as a leader in the field

Qualifications:

Education

  • PhD (preferred) in Quantitative Sciences such as Health Economics Mathematics Predictive Modeling Statistics Operations Research Physics Engineering or closely related field with 7 or more years of relevant experience; or

  • Masters degree with at least 9 years of relevant work experience

Required Experience and Skills

  • Demonstrated ability to lead and manage teams

  • Excellent written and verbal communication skills

  • Strong strategic thinking and problem-solving skills

  • Ability to work independently and interact effectively with a broad group of stakeholders

  • Ability to manage multiple priorities and deadlines

  • Ability to translate complex analyses into actionable insights

  • Experience in developing health economic models for decision-making

  • Strong expertise in oncology modeling

  • Experience with HTA and reimbursement submissions

BARDS2020

#eligibleforERP

Required Skills:

Commercialization Data Management Decision Models Healthcare Technology Health Economics Market Access Mathematics Medical Economics Mentorship Prioritization Product Development Researching Stakeholder Relationship Management Strategic Planning Strategic Planning Partnerships Strategic Thinking

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.

Learn more about your rights including under California Colorado and other US State Acts

The salary range for this role is

$210400.00 - $331100.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co. Inc. Rahway NJ USA also known as Merck Sharp & Dohme LLC Rahway NJ USA does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place introductions are position specific. Please no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

06/11/2026

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.


Required Experience:

Staff IC


About Company

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Merck & Co., Inc., Kenilworth, New Jersey, USA is known as “Merck” in the United States, Canada & Puerto Rico. We are known as “MSD” in Europe, Middle East, Africa, Latin America & Asia Pacific. We are a global biopharmaceutical leader with a diverse portfolio of prescription medicine ... View more

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