Senior Manager Manufacturing – Production Process Owners

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Manager Manufacturing Programs Production Process Owners

What you will do

Lets do this. Lets change the world!

In this vital role you will be a people leader and cross-functional integrator responsible for end-to-end process governance and execution support within Drug Product Supply operations at the Thousand Oaks campus.

This role ensures the site maintains a strong operating system for manufacturing readiness technical governance issue resolution and continuous improvement across multiple unit operations and enabling processes with accountability for driving alignment across key site forums priorities and decision-making bodies.

Key Responsibilities:

Leadership & Team Management

• Lead coach mentor and develop the manufacturing process owners within the manufacturing organization.

• Foster a culture of collaboration continuous improvement accountability and high performance across the team.

• Provide guidance performance feedback and support for career development plans for direct reports.

• Set clear priorities define role clarity and establish coverage plans so the PPO team can flex across site needs emerging issues and evolving operational demands.

Manufacturing Operations Management

• Ensure strong collaboration and coordination between Manufacturing and key partners such as Quality Facilities and Engineering Automation Supply Chain Maintenance and other site functions.

• Provide governance and execution support to ensure smooth compliant and reliable manufacturing operations.

• Manage and improve manufacturing processes to increase productivity reduce waste and maintain product quality and compliance.

• Strengthen process discipline documentation quality and operational readiness across site processes.

• Serve as an escalation point for complex execution topics ensuring issues are evaluated decisions are made with the right stakeholders and actions are closed with discipline.

Quality Compliance & Regulatory Oversight

• Ensure manufacturing activities are performed in compliance with cGMP and all applicable regulatory requirements and internal quality standards.

• Support inspection and audit readiness by ensuring appropriate documentation escalation pathways and governance transparency.

• Support site teams that own compliance-critical programs including aseptic compliance and validation-related execution by helping prioritize resources and drive timely resolution of issues.

• Ensure disciplined execution and timely closure of quality actions CAPAs and effectiveness verification activities in partnership with Quality and subject matter experts.

• Support and reinforce a strong safety culture and a safe working environment for all employees.

Process Optimization & Continuous Improvement

• Provide oversight and drive process improvement initiatives aimed at increasing efficiency improving reliability reducing costs and enhancing the drug product manufacturing process.

• Use lean manufacturing and other continuous improvement tools to identify opportunities and optimize operations.

• Analyze operational and quality data to identify trends solve complex problems and implement corrective actions.

Collaboration & Cross-Functional Communication

• Partner with site stakeholders to ensure readiness for new processes new products and major operational changes.

• Support risk identification issue resolution and execution readiness across impacted functions and unit operations.

• Facilitate or ensure strong facilitation of key site governance forums used to align priorities remove barriers and drive execution.

• Support the site project governance operating model including plant project prioritization by driving disciplined intake prioritization execution tracking and escalation when needed.

• Act as a point of contact for process owners during troubleshooting and resolution of manufacturing-related issues.

Technology Integration

• Stay current on technological advancements and assess opportunities for adoption in the plant.

• Support introduction and scale-up of new technologies equipment and systems that enhance production capabilities and improve operational performance.

• Partner cross-functionally to ensure technology-related changes are effectively planned implemented and sustained

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The manufacturing professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:

• Doctorate degree and 2 years of Manufacturing and Operations experience OR

• Masters degree and 6 years of Manufacturing and Operations experience OR

• Bachelors degree and 8 years of Manufacturing and Operations experience OR

• Associates degree and 10 years of Manufacturing and Operations experience OR

• High school diploma / GED and 12 years of Manufacturing and Operations experience

In addition to meeting at least one of the above requirements you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams projects programs or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

• Bachelors degree in Life Sciences Physical Sciences Engineering or a related technical discipline.

• 8 years of manufacturing operations technical operations or process support experience in biotechnology biopharmaceutical pharmaceutical or other highly regulated manufacturing environments.

• 6 years of leadership experience including direct people leadership and/or leadership of cross-functional teams programs or site-level initiatives.

• 2 years of experience managing coaching or developing direct reports technical teams process owners or matrixed contributors.

• Experience in Drug Product manufacturing operations including aseptic processing filling inspection packaging validation execution or manufacturing readiness.

• Strong working knowledge of cGMP operations and quality systems including deviations CAPAs change control effectiveness verification audit/inspection readiness SOPs batch records and controlled documentation.

• Demonstrated ability to lead governance forums drive cross-functional alignment prioritize competing site needs and ensure disciplined follow-through on actions and commitments.

• Experience troubleshooting complex manufacturing technical quality or operational issues in partnership with Quality Engineering Automation Supply Chain Maintenance Facilities and Technical Operations.

• Demonstrated ability to analyze operational and quality data identify trends drive root cause analysis and implement sustainable corrective and preventive actions.

• Experience applying lean manufacturing operational excellence value stream mapping capacity planning waste reduction or continuous improvement tools to improve manufacturing performance.

• Strong technical writing and communication skills with the ability to translate complex technical and operational topics into clear decisions actions and governance updates.

• Experience supporting implementation or sustainment of manufacturing technologies automation systems digital tools MES/electronic batch records data visualization platforms or process monitoring systems.

• Demonstrated ability to make sound decisions in complex ambiguous and highly regulated environments while balancing safety quality supply compliance and business priorities.

• Proven ability to build trust manage conflict effectively influence without authority and positively advance the culture of an organization.

• Strong business acumen including experience with goal setting resource planning budget awareness inventory control performance metrics and manufacturing operating systems.

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts

• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range