Senior Manager, Business Assessment Vaccines

ROLE SUMMARY

Business Assessment (BA) is an exciting highly collaborative and dynamic team of professionals responsible for generating the investment cases for all pipeline and business development decisions. BAs assessments are independent by design: our credibility rests on applying the same rigor whether the analysis supports or challenges the case for investment. BA sits within Pfizers Global Commercial Analytics (GCA) organization under the Chief Marketing Office a center of analytical excellence that unifies revenue forecasting across BD in-line and pipeline assets and elevates BAs strategic contribution across the full asset lifecycle. Our BA team is valued for proactive thought leadership epi-forecasting expertise innovative analytical capabilities and ability to communicate complex and dynamic information in clear concise and creative ways.

The BA Senior Manager owns discrete commercial assessments and forecasts end to end building the model framing the assumptions and defending both to inform investment decisions partnering with colleagues across Research & Development Global Commercial Strategy the US/ICO and Business Development (BD) to objectively evaluate internal pipeline and external opportunities against strategy and investment criteria. The Senior Manager works with a high degree of independence and is expected to be hands-on in the underlying models rather than directing others analysis ensuring thorough and consistent information to inform critical internal investment decisions and structure appropriate external deal terms.

The Senior Manager will also provide strategic input into trade-off decisions that may be required between investment options ensure consistency in assessment and forecasting approaches across external or internal investment options and present analysis and recommendations directly to executive governance bodies.

The role is anchored in vaccines where forecasting carries its own mechanics recommendation-driven uptake public and private market channels cohort-based populations seasonality and tender dynamics. Beyond vaccines the Senior Manager will also cover disease area opportunities across multiple therapeutic areas (oncology internal medicine inflammation and immunology) emerging technology platforms and novel modalities breadth of portfolio exposure that few commercial roles offer.

ROLE RESPONSIBILITIES

• Build and own assessments of pipeline and BD opportunities including epidemiology-based patient flow treatment exposure uptake and diffusion curves gross-to-net price build and risk-adjusted NPV collaborating closely with cross-functional partners to ensure the analysis is rigorous transparent and based on common and well-supported modeling techniques and assumptions
• Take and defend an independent position including recommending against an opportunity when the analysis does not support it and doing so on incomplete information when the decision timeline requires it. This independence is the core of BAs value to Pfizer.
• Gather input from key internal expert stakeholders on the potential clinical development plan or clinical profile and commercial evaluation (e.g. Global Commercial Strategy both early and global commercial Integrated Insights & Strategy Medical Affairs Global Access Strategy & Pricing Global Marketing/Regional leaders in the US and International Commercial Organization Research and Development Finance)
• Serve as commercial lead or co-lead of BD commercial subteams owning the integrated workplan framing the commercial narrative and what-must-be-true driving cross-functional alignment and delivering decision-ready recommendations that inform deal structure and terms
• Integrate in-line and BD/pipeline forecasts - connect BD/pipeline assessments to in-line assumptions cannibalization logic and Long-Range Forecast (LRF) revenue projections
• AI-enabled assessment - use AI tooling as a standard part of the workflow: evidence and literature synthesis competitive landscaping model QC and error-checking code-assisted analysis and drafting of executive materials. Cycle-time gains are expected without any loss of rigor and every assumption must remain traceable to its source.
• Scope and commission qualitative and quantitative primary market research with physicians key opinion leaders and patients managing consulting and vendor resources while abiding by rigorous internal customer engagement protocols
• Develop analytically supported recommendations to facilitate investment trade off decisions across therapeutic area opportunities as well as BD opportunities compared with internal pipeline investment
• Determine the appropriate level of rigor and external insights/research required depending on the timeline and decision to be made
• Work flexibly and comfortably on multiple therapeutic areas in a matrixed team as needed
• Support additional category and Pfizer portfolio-level projects (e.g. category strategy knowledge management best practice synchronization professional development) or enterprise level initiatives and evaluations using internal forecasts analyst reports and other secondary data

Basic Qualifications

• 6 years (Bachelors degree) or 5 years (Masters degree) of relevant experience in the biopharmaceutical industry life sciences consulting or a comparable analytical function
• Advanced Excel proficiency demonstrated ability to build audit and document multi-tab forecast and valuation models plus strong PowerPoint skills for executive-level materials
• Demonstrated hands-on experience building or owning quantitative commercial forecast and valuation models including patient-flow/epidemiology-based demand builds uptake curves gross-to-net pricing probability-of-success risk adjustment and NPV or rNPV valuation
• Experience using epidemiology literature analyst reports secondary/claims data primary research and pricing and market access inputs as the basis for a quantitative forecast
• Experience presenting analysis and recommendations directly to senior executive audiences including engaging commercial and research leaders at the appropriate points in the assessment process

Preferred Qualifications

• Prior experience in biopharma forecasting life sciences consulting financial services or other analytical professions
• MBA or life sciences advanced degree
• Experience in business development process specifically in opportunity identification commercial assessment and deal structure
• Vaccines forecasting experience including recommendation-driven uptake (e.g. ACIP or equivalent) public versus private channel dynamics publicly funded programs such as VFC cohort-based epidemiology seasonality and tender or multilateral markets
• Demonstrated use of AI/LLM tooling within an analytical workflow evidence synthesis model QC code-assisted analysis with assumptions kept traceable and auditable
• A track record of delivering an unfavorable or contrarian assessment that held up under senior scrutiny
• Proficiency in Python R or SQL for data handling automation and scenario analysis
• Experience influencing without direct authority in a matrixed organization and supporting or leading cross-functional teams under compressed timelines with incomplete information
• Working knowledge of healthcare and pharmaceutical industry trends competitor strategies dynamics in the US and other major global markets and the drug development process
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Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers develop and coach others oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Work Location Assignment:Hybrid

Other Job Details;

Last day to apply: September 22 2026

The annual base salary for this position ranges from $124400.00 to $207400.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN O-1 H-1B etc.) is not available for this role now or in the future.

To learn more about acceptable and prohibited uses of AI during the recruitment process please review our candidate AI-use guidelines available onPfizer Careers.

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