Senior Global Clinical Operations Program Director

Are you ready to lead global cell therapy programs that accelerate breakthrough medicines to patients As a Senior Global Clinical Operations Program Director you will guide the operational delivery of an ambitious clinical development plan translating strategy into measurable outcomes that matter for patients and the business. You will be a core leader on the Clinical Program Team partnering across disciplines to enhance the scientific and clinical relevance of our cell therapy assets.

In this role you will integrate strategy build feasibility and operational planning to deliver programs within defined parameters of scope quality budget and schedule. You will build clinical program structures champion creative approaches to compose and implementation and ensure robust governance. Can you see yourself orchestrating complex global studies and turning bold ideas into regulatory-ready results

This is your opportunity to influence direction at scale while developing high-performing teams and trusted partnerships that drive value. Accountabilities: Clinical Program Oversight: Lead end-to-end oversight of clinical program activities advancing relevant issues to senior governance and providing clinical operations expertise in feasibility country selection operational input to design risk management and external partner management. Use innovative design and delivery models to accelerate project start-up and informed decision-making.

Cross-Functional Leadership:

Partner with the Global Clinical Head and the Biometrics Team Leader to set clear direction and shared goals for Clinical Program Team members and clinical delivery teams ensuring cohesive execution.

Design and Delivery:

As a core member of the Clinical Program Team manage all clinical development deliverables to scope quality budget and time. Drive program strategy study design resourcing and risk mitigation that translate into predictable delivery and business impact.

igh-Performing Team Architecture:

Establish team structures governance and ways of working that enable a high-performing Clinical Program Team focused on outcomes and continuous improvement.

Line Management:

Provide line management to global clinical operational leaders at the study and program levels including Global Study Associate Directors or Global Study Directors and Global Program Directors aligned to the product teams deliverables. Serve as the line manager for Global Study Directors within your aligned product team.

Regulatory and Inspection Readiness:

Own the clinical operations components of regulatory submissions support regulatory interactions and reporting and lead clinical contributions to inspection readiness for marketing applications and post-registration maintenance.

External Interface and Alliances:

Act as the initial and program-level operational work with outsourced partners (CROs/AROs) and collaboration/alliance partners. Serve as AstraZenecas decision maker and critical issue point to ensure contract partners deliver to expectations.

Governance and Compliance:

Ensure timely compliance with company-wide governance controls including financial oversight planning and control continuous assurance and Clinical Trial Disclosure. Manage clinical planscost FTEs and timelinesin business reporting systems such as PLANIT. Improvement and Change Leadership: Lead or contribute to non-drug project work and cross-functional improvement initiatives. Be an early adopter and ambassador for new ways of working contribute as a Subject Matter Expert mentor and coach colleagues and actively network to share standard methodologies and takeaways.

Essential Skills/Experience:

• Bachelor of Science/Master of Science degree with a minimum of 10 years experience in related field or equivalent work experience.
• Extensive global drug development leadership or equivalent leadership experience demonstrated in a variety of roles.
• Extensive experience across the product life cycle with experience in Cell Therapy development and ideally across multiple therapeutic areas
• Clinical operations knowledge with strong track record of delivery
• Extensive knowledge of the clinical and pharmaceutical drug development process
• Validated ability to develop programs to meet business goals and to assess business risk versus potential value; ability to understand global business requirements
• Significant experience of program management and use of project management techniques in complex projects including resourcing financial management and business case development
• Proven ability to develop successful collaborations with internal collaborators and external partners
• Strong strategic influencing skills: ability to influence broadly within and outside the organisation
• Excellent written and verbal communication skills
• Proven collaboration and ability to work collaboratively across a wide range of teams
• Track record of planning prioritisation and delivery success
• Willingness to travel both domestic and international

Desirable Skills/Experience:

• Advanced degree is preferred
• Demonstrated ability to drive process improvement and/or functional work
• Cell Therapy Study Management Experience in a pharma/biotech setting
• Experience of implementing changes in ways of working that focus on increasing efficiency
• Regulatory submission experience
• Previous success of working in Japan and China to ensure delivery of global programmes to meet business needs
• Proven experience in leading teams through change
• Experience of and insight into the Clinical environment to be able to drive major improvement programs
• Experience in line management of leadership roles

When we put unexpected teams in the same room we spark ambitious thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Here you will join curious minds in an inclusive environment where open doors and open dialogue fuel progress. We combine scientific rigor with data technology and AI to tackle some of the worlds most complex diseases bringing unexpected teams together to spark bold thinking and swift delivery. You will collaborate with leading academics biotechs and industry partners build resilience through meaningful challenges and see your leadership translate directly into patient impactsupported by kind engaging leaders who value ambition and continuous learning.

Step into this pivotal role to shape the future of cell therapy and turn strategy into life-changing resultstake your next bold step today!

Date Posted

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Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.