Senior Director, Head of Technical Services, T1D CT Mfg Ops

Job Description

Job Title: Senior Director Head of Technical Services T1D Cell Therapy Manufacturing Operations

Department: Manufacturing Operations

Reports To: Vice President Type 1 Diabetes Manufacturing Operations

Location: Boston MA and Portsmouth NH

Work Model: Full time on site or hybrid eligible

Vertex is seeking a Senior Director Head of Technical Services to lead manufacturing-facing technical support for our Type 1 Diabetes Stem Cell Therapy Manufacturing Operations organization. This leader will oversee real-time GMP manufacturing support troubleshooting investigation support operational process monitoring manufacturing readiness and implementation of approved process changes. The role requires deep experience in cell therapy manufacturing strong people leadership and the ability to partner effectively across Manufacturing MSAT Quality Engineering and Supply Chain.

At Vertex we invest in scientific innovation to create transformative medicines for people with serious diseases. We are seeking an experienced and strategic leader to serve as Senior Director Head of Technical Services for T1D Cell Therapy External Manufacturing Operations organization.

This role leads the manufacturing-facing technical function responsible for enabling reliable compliant and efficient execution of complex cell therapy manufacturing processes across clinical and commercial operations. The Head of Technical Services provides leadership for real-time manufacturing support technical troubleshooting investigation support operational process monitoring manufacturing readiness and implementation of approved process changes in GMP operations.

This is a highly visible leadership role requiring expertise in cell therapy manufacturing strong cross-functional influence and a passion for translating process complexity into operational excellence.

Lead the Technical Services function supporting GMP manufacturing of cell-derived therapies for Type 1 Diabetes.

Provide technical leadership for cell therapy manufacturing operations

Serve as the senior technical escalation point for manufacturing issues affecting batch execution product quality cycle time or supply reliability.

Lead technical troubleshooting and support timely resolution of deviations investigations atypical events and process excursions.

Drive operational process monitoring and trend review to identify emerging risks improve execution consistency and enhance manufacturing performance.

Own Technical Services readiness for process changes campaign startup new product introduction and transferred processes entering GMP manufacturing.

Partner closely with Manufacturing Quality Assurance Quality Control Engineering Supply Chain Regulatory and CMC teams to support robust execution and inspection readiness.

Build develop and mentor a high-performing team of technical subject matter experts supporting manufacturing operations.

Foster a culture of quality accountability technical rigor collaboration inclusion and patient focus.

Success in this role requires building a strong and effective partnership with Manufacturing MSAT and Quality while maintaining clear accountability across functions. This role is expected to be primarily onsite given the importance of close partnership with GMP manufacturing operations and cross-functional teams supporting manufacturing execution.

Advanced degree in Bioengineering Chemical Engineering Bioprocess Engineering Cell Biology Molecular Biology Pharmaceutical Sciences or a related field.

15 years of relevant industry experience in biotechnology biopharmaceutical cell therapy or other advanced therapy manufacturing environments.

8 years of progressive people leadership experience including experience leading managers and cross-functional technical teams.

Demonstrated success leading manufacturing-facing technical support in a GMP-regulated environment.

Strong experience with deviations investigations troubleshooting batch support change implementation and operational problem-solving.

Proven ability to influence across Manufacturing Quality Engineering Supply Chain and process science organizations.

The ideal candidate will bring:

strong technical depth in advanced therapy manufacturing

a practical solutions-oriented approach to troubleshooting and execution support

strong judgment in high-stakes manufacturing environments

the ability to create clarity at functional interfaces especially between Technical Services Manufacturing and MSAT

a track record of building teams and developing leaders

a strong commitment to quality compliance and patient impact

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Guided by our commitment to patients we pursue advances in science technology and medicine to tackle diseases where we can make a meaningful difference.

Our teams bring together deep scientific expertise operational excellence and a bold sense of purpose. We are committed to fostering an environment where people can do their best work grow their careers and help deliver therapies that have the potential to transform lives.

At Vertex we embrace continuous learning and encourage employees to stay informed on advances in AI technology automation and industry trends. We seek talent who bring an external perspective demonstrate curiosity and sound judgment and thoughtfully adopt new capabilities that improve decision-making drive innovation increase efficiency and help deliver better outcomes for patients.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at