Senior Director, Financial Planning & Analysis R&D

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) Pompe disease and multiple DMD mutations. At Dyne we are on a mission to deliver functional improvement for individuals families and communities. Learn more at and follow us onXLinkedInandFacebook.

Role Summary:

The Senior Director FP&Aservesas a strategic finance leader responsible for advancing Dynes financial planning forecasting reporting and decision-support capabilities acrosstheResearch & Development organization. This rolepartnersclosely with Finance leadership the CFO functional leaders program and project teams and cross-functional stakeholders to translate scientific operational and corporate priorities into disciplined financial plans actionable insights and clear executive-level recommendations.

This leader is a strategic leader who inspires action manages interdependenciesallocatesresources effectively and influences decisions across functions. The role requires deep FP&Aexpertise strong business judgment and the ability to synthesize complex financial operational and portfolio information to guide planning investment decisions scenario modeling resource allocation and long-range financial strategy. This leaderstrengthensscalable FP&A processes tools reporting and operating rhythms to support Dynes continued growth and mission of delivering meaningful outcomes for patients.

This role is based in Waltham MA.

Primary Responsibilities Include:

• Lead annual budgeting quarterly forecasting long-range planning and scenario modeling processes acrossR&Dfunctions: Research Clinical Development RegulatoryandPortfolioStrategy&Operationsand thecross-functionalprogramleadership team
• Partner with the VP FP&A to develop manage and continuously improve Dynes enterprise planning calendar planning assumptions financial models templates reporting packages and governance processes
• Serve as a trusted finance business partner toR&Dfunctions: Research Clinical Development Regulatoryand Portfolio Strategy & Operationsand the cross-functional program leadership teamprovidingfinancial insights that support strategic decision-making portfolio prioritization operating discipline and resource allocation
• Translate program timelines clinical development plans headcount plans vendor commitments and functional priorities into clear financial forecasts and actionable recommendations
• Partner closely with the program leadership team and Clinical Operations to develop and manage a live clinical trial forecasting model that clearlyidentifieskey assumptions and drivers enabling robust scenario planning and informed investment decisions
• Lead program- and function-level budget reviews challenging assumptionsidentifyingrisks and opportunities and ensuring alignment between financial plans corporate goals program milestones and functional priorities
• Develop andmaintainrobust financial models dashboards and reporting tools that provide visibility into spend cash runway operating performance clinical and program costs headcount and key business drivers
• Prepare and present executive-ready financial analyses variance explanations forecast updates and recommendations for Finance leadership the CFO senior leadership and other governance forums as needed
• Lead monthly and quarterly actuals reporting variance analysis accrual support and close-related FP&A activities in partnership with Accounting Procurement and functional budget owners
• Partner with Accounting to ensureappropriate expenserecognition accrual accuracy budget-to-actual transparency and alignment with US GAAP SOX requirements and company policies
• Support strategic analyses related to capital planning cash runway business development opportunities program investment decisions launch readiness and other enterprise priorities
• Identify implement and scale process improvements that increase forecast accuracy planning discipline reporting consistency transparency and efficiency across the FP&A function
• Support implementation optimization and adoption of financial planning systems and enterprise tools including planning applications reporting dashboards and related integrations
• Foster accountability and financial ownership across the organization by enabling clear communication practical guidance and consistent operating rhythms with functional leaders and budget owners
• Build coach and develop FP&A talent as the function evolves creating a collaborative inclusive high-performing team culture grounded in Dynes values
• Model Dynes core values by leading with purpose accountability transparency collaboration sound judgment and a commitment to continuous improvement
• Perform ad-hoc financial analysis and support special projects asrequired

Education and Skills Requirements:

• Bachelors degree in Finance Accounting Economics Business or a related field
• Advanced degree CPA CFA or MBA preferred
• 15 years of progressive finance FP&A corporate finance strategic finance or related experience preferably in biotechnology pharmaceuticals life sciences or another high-growth R&D-driven environment
• 8 years of experience leading people teams major workstreams or a finance function directly or through cross-functional leadership
• Strong understanding of biotechnology financial drivers including R&D investment planning clinical developmentspendROI analysis program timelines vendor commitments headcount planning operating expense management and cash runway considerations
• Experience building andmaintaininglive clinical trial forecasting models with the ability toidentifykey cost assumptions and drivers and support scenario planning across clinical programs
• Demonstrated ability to lead annual planning forecasting long-range planning management reporting scenario analysis and executive-level financial presentations
• Experience partnering with R&D Clinical Development CMC Technical Operations Commercial G&A or other functional leaders to align operating plans with corporate strategy and financial targets
• Strong working knowledge of US GAAP SOX requirements accrual processes budget-to-actual reporting financial controls and close-related FP&A responsibilities
• Deep financial modeling analytical and problem-solving skills with the ability to synthesize complex data into clear insights recommendations and trade-off decisions
• Demonstrated ability to influence senior stakeholders reconcile multiple perspectives manage interdependencies and drive outcomes in a matrixed environment without relying solely on formal authority
• Proven ability to build scalable processes reporting infrastructure financial models dashboards and planning tools that improve transparency accountability and decision-making
• Strong executive presence and communication skills including the ability to prepare and deliver conciseaccurate and compelling materials for senior leaders and governance forums
• Highproficiencywith Microsoft Office products especially Excel and PowerPoint; experience with financial planning systems ERP systems and reporting tools preferred
• Strong organizational and project management skills with the ability to manage multiple priorities meet tight deadlines andmaintainhigh-quality work in a fast-paced environment
• Sound judgment high integrity attention to detail and commitment to compliance confidentiality and financial discipline
• Collaborative solutions-oriented leader who builds trust empowers others promotes accountability and contributes to a positive and inclusive team culture
• Excitement about Dynes mission operating environment and core values

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The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education experience job-related knowledge and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job the level of knowledge and skill typically required and the scope of responsibility but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned including work in other functional areas to cover absences or relief to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age color disability gender national origin race religion sexual orientation veteran status or any classification protected by federal state or local law.