Senior Director, Epidemiology

Summary of Role:

The Senior DirectorEpidemiologyis a leader who shapesevidencegeneration strategy across therapeutic areas while driving technical excellence and cross-functional collaboration. This role combines deep epidemiologicexpertisewith executive presence leading teams to deliverinnovativerealworldevidence that advises critical business decisions throughout the product lifecycle with an emphasis on applications in Clinical Development Regulatory and a key member of the EpidemiologyandReal WorldScienceDepartment leadership team you will influence both internal strategy and external scientific discourse while building and developing high-performing teams.

Accountabilities:

Strategic Leadership & Execution

• Develop and implement comprehensive epidemiology strategic plans aligned withcorporateobjectivesacross assigned therapeutic areas

• Advise the planning prioritization and execution of epidemiology deliverables including systematic literature reviews realworld data analyses and observational studies/disease registries

• Optimizeresource allocation and operational efficiency ensuring deliverables meet quality budget and timeline requirements while incorporatinginnovativemethodologies

• Collaborate with thedepartment headon department-level strategic planning including workforce planning external resource evaluation andrealworlddata source assessment

• Navigate organizational ambiguities and policy complexities to ensure successful execution of critical initiatives

• Identifyprocess gaps and lead the development and maintenance of Standard Operating Procedures and Process Guides

Cross-Functional Collaboration

• Serve as the epidemiologyleadon cross-functional therapeutic area teams partnering with Clinical Development Pharmacovigilance Regulatory Affairs Medical Affairs Commercial/MarketingandHEOR

• Engage proactively with senior and executive leadership to integrate epidemiologic evidence into strategic decision-making throughout the product lifecycle

• Break down functional silos through influence conflict resolution and negotiation to achieve shared objectives

• Represent thedepartment in high-level corporate meetings and critical initiatives

• Lead or contribute to R&D and corporate process improvement initiativesfinding opportunities to enhance efficiency and impact

• Assess and address diverse team member needs translating sophisticated epidemiologic concepts for varied audiences

• Provide executive-level presentations and recommendations that shape business strategy

Technical Excellence & Innovation

• Serve as a recognized technical authority in epidemiologic methods including observational study design causal inference safety signal quantification and disease epidemiology

• Apply sophisticated analytical approaches using SAS R Pythonor other statistical software to extract meaningful insights from sophisticated realworld data sources

• Ensure all epidemiology deliverables reflect current standard processes and methodological advancements in pharmacoepidemiology

• Provide experienced technical guidance and scientific rigor across systematic literature reviews database studies and registry analyses

• Contribute epidemiologicexpertiseto study protocols case report forms (CRFs) clinical conference materials and regulatory documents

• Author and review scientific manuscripts abstracts and presentations based on observational study datamaintaininghigh publication standards

• Work with authors referees and in-house reviewers to ensure scientific quality and accuracy

• Stay current with emerging methodologies and data sources recommending innovations that advance departmental capabilities

Leadership & People Development

• Provide direct line management and leadership for Epidemiologists within assigned therapeutic areas fostering a culture of scientific excellence and collaboration

• Mentor team members in epidemiologic methods critical thinking and professional development supporting their growth as technical authorities and leaders

• Actively teach and mentor colleagues both within and outside thedepartment contributing to organizational capability building

• Lead vendor and contractor relationships ensuring external partners deliver high-quality work aligned with strategic objectives

• Champion professional development for self and direct reports creating opportunities for skill enhancement and career advancement

• Identifyand develop future leaders within thedepartment

• Conduct performance evaluations provide constructive feedback and support career progression for team members

• Build a diverse inclusive high performingteam environment that values different perspectives and approaches

External Influence & Thought Leadership

• Represent the company and Epidemiology Department in interactions with regulatory authorities Scientific Advisory Boards and other external partners

• Influence industry standards and guidelines through active leadership in professional societies industry associations and regulatory working groups

• Build the companys reputation as a leader in rare disease epidemiology through publications presentations and scientific discourse

• Leverage deepexpertisein rare disease epidemiology to advance understanding of disease burden natural history and treatment outcomes

• Establish andmaintainrelationships with key opinion leaders and external research collaborators

• Contribute to the broader scientific community through peer review conference participation and collaborative research initiatives

• Serve as a spokesperson for the organization at scientific conferences and industry events

• Travel may berequired(up to 10%).

Required Skills and Education:

• PhD / DSc / DrPH in Epidemiology withminimum12years post-graduation experience or MPH/MSc in Epidemiology withminimum15years post-graduation experience

• Minimum 6years ofdirectline management experience of multiple reports

• The duties of this role aregenerally conductedin an office is typical of an office-based role employees must be able with or without an accommodation to: use a computer; engage in communications via phone video and electronic messaging; engage in problem solving and non-linearthought analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

• Demonstratedexpertisein epidemiologic methods observational study design causal inference andrealworlddata analysis

• Proficiencywith SAS R Pythonor other statistical software packagesThorough and current knowledge of pharmacoepidemiology methods and applications

• Strong understanding of safety signal quantification and risk-benefit assessment

• Consistent recordof publications in peer-reviewed journals

• Exceptional oral and written communication skills with ability to present sophisticated information to diverse audiences

• Strong attention to detail scientific rigor and commitment to quality

• Experience working optimally in cross-functional matrixed environments

• Demonstrated ability to influence senior partners and drive consensus

• High degree of self-motivation organization and adaptability

• Comfort working in a fast-moving environment with evolving priorities

Desired Skills:

• Deepexpertiseanddemonstratedexperience in rare disease epidemiology

• Knowledge of drug development processes and regulatory requirements across the product lifecycle

• Experience collaborating with regulatory authorities (FDA EMA etc.)

• Active leadership roles in professional societies (ISPE ISPOR etc.) or industry associations

• Track recordof thought leadership through publications presentations and external engagement

• Experience with multiple realworld data sources including claims databases electronic health records and patient registries

• Experience in registry development implementation and analysis

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of four days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $229047 to $343571. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

At AstraZenecas Alexion division youll find an environment where innovation thrives. Our commitment to rare diseases means your work will have a profound impact on patients lives. With a rapidly expanding portfolio and an entrepreneurial spirit youll be part of a team that values connection and collaboration. We empower our employees through tailored development programs that align personal growth with our mission. Join us in driving change with integrity while celebrating diversity and innovation.

Ready to make a difference Apply now to join our team at Alexion!

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.