Scientist, In Vivo High Throughput Screening & Analytics

Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But were not finished yet.

Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.

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The Scientist Research High Throughput Screening & Analytics (HTSA) role is a technical and scientific specialist within Kite Research who designs executes analyzes and improves high-throughput screening scale-down and analytical workflows that support in vivo lentiviral vector research programs. The role generates high-quality experimental data and scientific insight across screening campaigns automated assay workflows vector and cell-based characterization and data analysis pipelines. Operating with limited guidance the Scientist applies scientific judgment to troubleshoot methods interpret complex data sets recommend next steps and communicate outcomes clearly to HTSA and cross-functional partners.
This role is expected to combine hands-on laboratory execution with automation-minded workflow development and data-driven decision making. The Scientist will partner with Discovery Process Development Analytical Development and other Kite Research stakeholders to deliver reproducible decision-enabling data that advances early product and platform development.

Key Responsibilities

• Design plan and execute high-throughput screening and analytical experiments with limited guidance including miniaturized and scale-down assay formats that support vector process analytical and functional characterization needs.
• Develop optimize and troubleshoot automated or semi-automated laboratory workflows using liquid handling scheduling plate-based assay and data capture platforms to improve throughput reproducibility and data quality.
• Execute and analyze cell-based vector-based and analytical assays relevant to in vivo CAR-T and lentiviral vector research including transduction vector performance binding expression potency and related characterization endpoints as appropriate to project needs.
• Build or improve data reduction visualization and reporting workflows using tools such as Python R SQL VBA JMP Prism Spotfire or equivalent platforms; apply appropriate statistical and analytical methods to support candidate selection and project decisions.
• Analyze and interpret complex experimental data; draw logical evidence-based conclusions and recommend next steps that enable rapid project decisions across HTSA Analytical Development Process Development and Discovery.
• Identify and solve technical problems requiring ingenuity and creativity including assay variability scale-down translation automation failures data integrity issues and workflow bottlenecks.
• Prepare and present clear technical summaries reports data packages and presentations for functional and cross-functional audiences; contribute to technical reports publications patent-supporting materials or regulatory documentation as appropriate.
• Collaborate frequently across Kite Research to align screening plans sample logistics assay design automation needs and deliverables with broader program objectives.
• Maintain accurate traceable and well-organized experimental records and data files in accordance with Kite documentation data integrity safety and quality expectations.
• Share technical expertise train colleagues on methods or automation workflows and contribute to a collaborative problem-solving culture within HTSA and partner functions.

Basic qualifications:

• MS with 4 years of relevant experience; or
• BS with 6 years of relevant experience.

Preferred Qualifications

• PhD or PharmD in Biotechnology Biology Biochemistry Molecular Biology Immunology Biomedical Engineering Bioengineering or a related scientific discipline with 0 years of relevant experience; or
• MS with 4 years of relevant experience; or
• BS with 6 years of relevant experience.
• Advanced and current knowledge of scientific principles and techniques in biotechnology molecular biology cell biology immunology biomedical engineering analytical development or a related field.
• Demonstrated ability to independently design and execute experiments troubleshoot methods interpret data and define next steps under limited guidance.
• Experience with high-throughput screening assay miniaturization laboratory automation automated liquid handling or scale-down experimental systems.
• Hands-on experience with mammalian cell culture plate-based assays vector or cell-based characterization assays and/or analytical method development in a biotechnology pharmaceutical or academic research environment.
• Experience analyzing and summarizing complex experimental data using appropriate statistical visualization or workflow automation tools.
• Ability to work effectively in a fast-paced cross-functional research environment and communicate scientific findings clearly to technical and non-technical stakeholders.
• Strong documentation practices attention to data quality and commitment to laboratory safety reproducibility and rigorous experimental execution.
• Ability to provide technical advice share best practices and help train or mentor less experienced colleagues in laboratory methods automation workflows or data analysis approaches.
• Relevant experience may include high-throughput screening assay development laboratory automation vector or cell-based characterization analytical development data analysis or applied research in biotechnology pharmaceutical academic or related R&D environments.

• Experience with lentiviral vector production characterization or functional evaluation.
• Experience with primary immune cell or T-cell assays transduction workflows flow cytometry ELISA/AlphaLISA BLI/Octet internalization binding or potency-oriented assay formats.
• Experience implementing or troubleshooting liquid handlers schedulers or integrated systems such as Tecan EVO/Fluent Hamilton STAR Beckman Biomek CyBio FeliX Opentrons HighRes BioSero Green Button Go Agilent Velocity11 or comparable platforms.
• Experience programming or scripting in Python R SQL VBA MATLAB or related tools to automate analysis quality control visualization or reporting.
• Familiarity with Design of Experiments (DOE) multivariate optimization assay qualification concepts or statistical methods used in screening and analytical development.
• Experience working in a biotechnology or cell/gene therapy environment with cross-functional partners in Discovery Process Development Analytical Development or Translational Research.

• Create Inclusion - knowing the business value of diverse teams modeling inclusion and embedding the value of diversity in the way they manage their teams.
• Develop Talent - understand the skills experience aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow develop and realize their purpose.
• Empower Teams - connect the team to the organization by aligning goals purpose and organizational objectives and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

The salary range for this position is: $133195.00 - $172370.00. Kite considers a variety of factors when determining base compensation including experience qualifications and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus discretionary stock-based long-term incentives (eligibility may vary based on role) paid time off and a benefits package. Benefits include company-sponsored medical dental vision and life insurance plans*.

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and kill tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:

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