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Scientist II LC-MSMS Bioanalysis (Method Development)

KCAS Bio

Job Location:

Kansas City, MO - USA

Monthly Salary: Not provided by the employer

Posted: 8 November 2026 (Yesterday)

Application Deadline: 5 February 2027

Vacancies: 1 Vacancy

Job Summary

Performing critical work that impacts our industry and our worlds health while problem solving and innovating in the field that is what Scientists at KCAS Bio get to do every day. If that gets you excited too then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist II in the Mass Spec Bioanalysis Development group at KCAS you get to further our mission by applying your knowledge of bioanalytical and scientific principles to independently execute study activities from sample preparation and LC-MS/MS analysis through data processing while supporting method development qualification and optimization. You will utilize your scientific foundation to assess data integrity troubleshoot technical challenges and deliver high-quality results with limited oversight.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid ChromatographyTandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery preclinical and clinical studies including the bioanalysis of drugs and metabolites biomarkers and active endogenous compounds in biological fluids and tissues.

In this role we will rely on you to:

Execute study activities including sample preparation (extractions enrichments/affinity capture digestions) LC-MS/MS analysis and data processing with limited supervision
Support method development qualification and optimization activities
Troubleshoot technical issues and propose solutions with limited guidance
Analyze data and prepare summaries for senior scientists to aid in client updates
Ensure compliance of study activities with pertinent portions of study protocol SOPs & regulatory requirements
Communicate study progress and risks to senior staff
Provide informal guidance to junior staff as needed
Perform all aspects of the job in a way that supports company brand and supports company mission vision and values

To qualify specifically for this role you will have:

Bachelors or masters in chemistry Biochemistry or chemical/biochemical engineering or related field with at least 24 years of experience with LC-MS/MS
Hands-on experience with bioanalytical sample preparation quantitative LC-MS/MS and chromatography
Experience supporting method development qualification and troubleshooting
Experience with small molecule analysis; proteins peptides or biomarkers experience preferred
Familiarity with reversed phase or HILIC chromatography and standard bioanalytical workflows
Experience working in a regulated environment (GLP/GxP) preferred

Depending on your background and qualifications we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.

(Please note this is a representative summary of responsibilities not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment are purpose- and values-driven embrace constant development and supportive leadership and enjoy being part of innovative work.

WHAT YOULL GET

Our benefits include and extend beyond the traditional package. At KCAS Bio you will enjoy company sponsored events like food trucks family days and spirit will grow in your career with KCAS will be able to connect with like-minded employees to further KCAS Bios approach to key areas such as wellness inclusion and community will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio

WHO WE ARE

We are a fast-growing contract research organization (CRO) headquartered in Kansas City pioneering the latest drug development in both human and animal health for our expertise is growing and so is our need for great people to work in nimble empowered teams committed to one anothers growth. At KCAS Bio we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things we provide equal employment opportunities without regard to race color religion national origin ancestry marital status veteran status age disability pregnancy genetic information sex sexual orientation gender identity or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs observances and practices. Anyone who needs reasonable accommodation may send an email to emailprotectedor call (for TTY assistance call 711) and ask for Human Resources.

IND123

We may use artificial intelligence (AI) tools to support parts of the hiring process such as reviewing applications analyzing resumes or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed please contact us.

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About Company

KCAS Bio

As a full-service bioanalytical CRO and biomarker partner, KCAS Bio helps accelerate drug development in the pharma and biopharma industries with large and small molecule bioanalysis.

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