Scientist I, In Vitro Technologies Discovery Biotherapeutics

Discovery Biotherapeutics and Genetic Medicine at AbbVie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and engineering. The successful candidate will be responsible for the design and execution of in vitro display technologies for lead antibody identification and optimization and will collaborate to generate stage-gate appropriate in vitro cellular and in vivo data packages supporting proof-of-concept (PoC). This role leverages scientific expertise to develop and implement research supporting the discovery optimization and mechanistic understanding of the molecular pharmacology of therapeutic molecules across Therapeutic Areas. The ideal candidate should be able to analyze document and report data effectively and possess excellent communication skills with comfort presenting in group settings.

Qualifications :

Education: BS or MS in Biology or a related field with typically 5 years of experience (BS) or 2 years of experience (MS) in a pharmaceutical and/or relevant research environment.

Required Skills & Experience

• Strong molecular biology skills (e.g. molecular cloning)
• Familiarity with sequence analysis tools (e.g. Geneious Genedata PipeBio)
• Experience with biologics antibodies antibody fragments and mimetics
• Experience with bacterial cell culture
• Solid understanding of protein structure and function
• Excellent oral and written communication skills
• Ability to engage internal and external scientific leaders in collaborative research
• Strong organizational skills with the ability to manage multiple projects simultaneously
• Team player who thrives in a fast-paced multi-disciplinary environment
• Ability to adapt to rapid changes in project priorities and timelines
• Proficiency with MS Office Suite (Excel PowerPoint Word)

Preferred Skills & Experience

• Hands-on experience with in vitro antibody discovery display technologies (e.g. phage display yeast display)
• Direct experience with binding assays (e.g. ELISA flow cytometry)
• Experience in antibody engineering and optimization (e.g. affinity modulation liability engineering humanization)
• Experience with antibody library design and construction
• Experience in mammalian cell culture
• Experience with automation of biologics discovery processes
• Proficiency with Prism Geneious Sequencher and/or Genedata
• Familiarity with computational approaches and an ability to work independently and in partnership with AI/ML and Digital Transformation teams to amplify in vitro technology workflows and contribute to AbbVies AI/ML infrastructure

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors  including  geographic location and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. 
• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to  participate in our short-term incentive programs.  

Note: No amount of pay is  considered to be wages or compensation until such amount is earned  vested and determinable. The amount and availability of  any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a   particular employee  remains in the Companys sole and absolute discretion unless and until paid and may be  modified at the Companys sole and absolute discretion  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time