Scientist – Erythroid Biology

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist Erythroid Biology

What you will do

Lets do this. Lets change the this vital role you will. A Scientist at Amgen is responsible for designing and conducting experiments analyzing results and interpreting data. They prepare technical reports summaries and protocols and present study results at team meetings. They also assist in maintaining lab equipment troubleshooting issues and ensuring safety protocols are adhered to.

Responsibilities:

Design and execute in vitro and ex vivo assays to evaluate siRNA delivery and function

Develop human primary cell-based systems

Support target validation and mechanism-of-action studies for siRNA therapeutics

Collaborate with Delivery/chemistry teams Translational and biomarker teams

Establish and optimize Flow cytometry panels qPCR / RNA-based readouts

Contribute to IND-enabling studies and data packages

Basic Qualifications:

Doctorate degree

Masters degree and 2 years scientific experience

OR

Bachelors degree and 4 years scientific experience

Preferred Qualifications:

Experience with siRNA / RNA therapeutics (delivery or functional assays) Erythroid biology and hematopoiesis.

Strong background in Flow cytometry (multi-color) Cell-based functional assays

Familiarity with gene expression (qPCR RNA assays) target engagement assays Experience working in cross-functional drug discovery teams

Knowledge on Hemoglobinopathies conjugated delivery systems CRISPR or gene editing is a plus

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen anticipates accepting applications however we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race color religion sex sexual orientation gender identity national origin protected veteran status or disability status.

Salary Range