Scientist, Analytical Technical Operations

The Role

The Moderna Analytical Technical Operations (ATO) team is seeking a Scientist to lead operational method development and enable the transition of analytical methods from development into robust scalable and high-throughput laboratory execution. This is an onsite role based at Modernas Technology Center campus in Norwood MA.

You will serve as a critical scientific interface between Analytical Development and ATO combining technical expertise in LC/MS chromatography microfluidic methods automation and high-throughput methodologies with a strong understanding of sample demand turnaround time equipment capacity data flow and routine execution requirements. You will drive method optimization technology transfer troubleshooting and lifecycle improvements supporting characterization in-process release and stability testing across Moderna programs.

Heres What Youll Do

• Lead operational method development focused on robustness reproducibility throughput automation compatibility data integrity and long-term sustainability.
• Translate Analytical Development methods into standardized and scalable workflows suitable for routine high-volume testing environments while preserving scientific intent and required performance.
• Design and execute method studies supporting optimization performance characterization comparability pre-validation transfer and operational readiness.
• Provide technical expertise in LC/MS and separation sciences including HPLC/UHPLC capillary electrophoresis microfluidic platforms method execution data interpretation and troubleshooting.
• Advance microfluidic analytical methods including LabChip or comparable platforms to improve speed sample efficiency consistency and scalability.
• Develop automation-ready workflows including sample preparation and analytical methods compatible with liquid handlers robotic platforms plate-based execution and integrated data systems.
• Apply high-throughput principles to optimize batching instrument utilization analyst touch time cycle time and overall laboratory capacity.
• Serve as a primary scientific interface with Analytical Development by engaging early in method design and communicating operational requirements for volume run time controls standards equipment data review automation and transferability.
• Lead or support analytical technology transfer including transfer strategy execution acceptance criteria knowledge transfer training documentation and post-transfer monitoring.
• Drive complex technical troubleshooting and investigations involving methods instrumentation reagents samples data and workflow interactions using structured root cause analysis and experimental design.
• Partner across Process Development Formulation Sciences Quality Control Digital Automation Laboratory Engineering and external organizations to ensure end-to-end method and technology readiness.
• Create clear technical documentation including protocols reports transfer packages work instructions risk assessments and training materials that enable consistent execution.
• Mentor colleagues and strengthen organizational capability in method science operational development technology transfer automation and data-driven problem solving.
• Drive continuous improvement and method lifecycle management through performance monitoring modernization change implementation and sustainable corrective and preventive actions.

Heres What Youll Need (Basic Qualifications)

• Education: PhD in Analytical Chemistry Biochemistry Chemical Engineering Pharmaceutical Sciences Molecular Biology or a related scientific discipline or a Masters or Bachelors degree with directly applicable industry experience.
• Experience: Demonstrated experience in analytical method development optimization transfer validation or pre-validation troubleshooting and lifecycle support.
• LC/MS and chromatography: Hands-on experience with LC/MS and liquid chromatographic techniques including method performance assessment data interpretation and troubleshooting.
• Operational method development: Experience translating scientific method requirements into reliable routine execution while accounting for volume capacity scheduling turnaround time training and executional robustness.
• Technical leadership: Demonstrated ability to independently design studies analyze data solve complex problems manage multiple priorities and influence outcomes across cross-functional teams.

Heres What Youll Bring to the Table (Preferred Qualifications)

• Advanced analytical platforms: Experience with microfluidic capillary electrophoretic plate-based or comparable high-throughput analytical technologies including LabChip or similar platforms.
• Automation and high throughput: Experience designing implementing or improving automated or semi-automated laboratory workflows using liquid handlers robotic systems integrated workcells or automated data processing.
• Advanced therapeutic modalities: Experience supporting mRNA oligonucleotide gene therapy biologics vaccines lipid nanoparticles or other advanced therapeutic modalities.
• Method lifecycle and regulated environments: Knowledge of analytical procedure lifecycle management data integrity GMP/GLP expectations and phase-appropriate method control.
• Digital laboratory systems: Experience with LIMS ELN chromatography data systems laboratory scheduling tools automated data pipelines or instrument integration.
• External collaboration: Experience partnering with contract laboratories external development or manufacturing organizations instrument vendors or automation providers.
• Ways of working: Strong scientific judgment technical writing collaboration communication and the ability to translate complex scientific concepts into practical operational solutions.
• Mindset: Proactive curious data-driven and committed to quality operational excellence continuous improvement and Modernas mission.

Our Working Model

As we build our company we have always believed that an in-person culture is critical to our success. This role is 100% onsite reflecting the importance of being physically present to support the work collaborate closely with colleagues and contribute to our site-based operations.

Working onsite enables real-time collaboration strong team connections direct mentorship and the hands-on partnership needed to deliver our mission. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.

Moderna is a smoke-free alcohol-free and drug-free work environment.

Pay & Benefits

At Moderna we believe that when you feel your best you can do your best work. Thats why our benefits and well-being resources are designed to support youat work at home and everywhere in between.

• Competitive healthcare plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being with access to fitness mindfulness and mental health support
• Family planning benefits including fertility adoption and surrogacy support
• Generous paid time off including vacation volunteer days sabbatical global recharge days and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $109200.00 - $174600.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individuals position within the salary range will be based on several factors including but not limited to specific competencies relevant education qualifications certifications experience skills performance and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus other incentive compensation or equity award subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine we invite you to visit to learn more about our current opportunities.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.

Accommodations

Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws including the Export Administration Regulations (EAR). As such employment is contingent upon the applicants ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements only individuals who qualify as U.S. persons (citizens permanent residents asylees or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

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