Scientist 3

We are seeking a motivated and detail-oriented Scientist 3 to join our Formulation this hands-on laboratory role you will independently execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery. The successful candidate will be a collaborative team player with strong technical and data analysis skills who is ready to contribute to our non-viral delivery platform.

The Opportunity:

• You will independently execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) encapsulating nucleic acids for in vitro and in vivo studies.

• You will lead DoE-based screening campaigns directed toward discovering LNPs setting LNP composition specifications and optimizing LNP formulations..

• You will collaborate cross-functionally with internal teams (biology analytics chemistry and project management) to advance programs.

• You will support early-stage formulation development and downstream processing activities including cryoprotection scale-up and stability studies as needed.

• You will maintain detailed records documenting formulation activities and results.

• You will analyze interpret and present experimental data in group meetings.

• You will troubleshoot formulation challenges and continuously improve workflows.

This is an onsite role based in San Diego CA.

Relocation benefits are not being offered for this position.

Who You Are:
(Required)

• You have a PhD in Chemistry Biochemistry Chemical Engineering or a related discipline with relevant academic and/or biopharma industry experience; OR a Masters degree in Chemistry Biochemistry Chemical Engineering or a related discipline with 3 years of industry experience.

• You have 2 or more years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA siRNA or DNA) for in vitro and in vivo studies.

• You have are highly proficient with standard LNP characterization methods including Dynamic Light Scattering (DLS) Zeta potential and Ribogreen assays.

• You have a demonstrated level of expertise in MS Excel; hands-on experience with statistical and data analysis software (e.g. JMP Prism)

• You have a demonstrated level experience in the LNP field in the form of publications and/or patent filings.

Preferred:

• You have experience with Tangential Flow Filtration (TFF) and bioconjugation chemistry is highly desirable.

• You have experience working in an FDA-regulated environment

• You have strong communication skills including the ability to communicate with all levels within the organization; you are hands-on self-directed organized conscientious.

• You have strong problem-solving judgment and decision-making skills

• You have strong time management and organizational skills in a dynamic continually changing environment; you have the ability to respond effectively to sensitive inquiries customer inquiries or complaints as well as communicate effectively both orally and in writing with management peers and individuals.

• You have the ability to work effectively exhibit a professional manner and establish constructive working relationships.

• You have excellent written and verbal communication skills

The expected salary range for this position based on the primary location of San Diego CA is $89900 - $166900. Actual pay will be determined based on experience qualifications geographic location and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ promote and otherwise treat any and all employees and applicants on the basis of merit qualifications and competence. The companys policy prohibits unlawful discrimination including but not limited to discrimination on the basis of Protected Veteran status individuals with disabilities status and consistent with all federal state or local laws.

If you have a disability and need an accommodation in relation to the online application process please contact us by completing this form Accommodations for Applicants.