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Research Scientist I- #26-22930

US Tech Solutions

Job Location:

Lexington, KY - USA

Hourly Salary: USD 39 - 40

Posted: 29 September 2026 (Yesterday)

Application Deadline: 27 December 2026

Vacancies: 1 Vacancy

Job Summary

Duration: 12 months (extension possibility)
Job Description:
Top Skills Per Mgr:

Lab experience in formulation of oligonucleotides or antibodies for subcutaneous injection
Hands on analytical characterization of oligonucleotides or antibodies/protein
Experience with developability assessments including evaluation of parameters like maximum solubility viscosity osmolality limited chemical and physical stability

The Associate Research Scientist Contractor RNAi Formulations will be based within Non-Viral Delivery (NVD) in Research & Early Development. This is a laboratory-based role focused on hands-on RNAi formulation development biophysical and analytical characterization and support of oligonucleotide delivery activities for injectable therapeutics.

Relationships

Reports to the US Team Manager for Nucleic Acid Delivery Formulations and Bioanalysis. Interacts closely with peers and cross-functional partners specializing in non-viral delivery formulation development oligonucleotide chemistry stability assays PK bioanalysis CMC and external collaborators.

Essential Functions

Support the development and characterization of preclinical RNAi and oligonucleotide formulations across portfolio and platform projects.

Execute hands-on formulation preparation biophysical characterization analytical testing and data analysis to support formulation selection and developability assessments.
Establish and run screening assays for oligonucleotides in early discovery including formulation performance solubility viscosity osmolality degradation and stability assessments.
Contribute to high-throughput and design-of-experiments approaches for formulation optimization where applicable.
Support long-term storage and stability evaluations for RNAi conjugates and oligonucleotide formulations.
Maintain accurate experimental documentation and communicate findings through written summaries reports and internal presentations.
Collaborate with internal stakeholders and external partners to support project deliverables and timelines.
Identify technical gaps propose practical solutions and contribute to continuous improvement of formulation and characterization workflows.
Thrive in a multidisciplinary fast-paced research environment with competing priorities and tight deadlines.

Qualifications And Skills

MS with approximately 3 years of relevant experience or PhD with 1-3 years of relevant experience in pharmaceutical sciences formulation sciences chemical engineering biophysics analytical chemistry oligonucleotide delivery or a related discipline.
Hands-on experience with oligonucleotide or antibodies/proteins formulation and characterization is strongly preferred.
Experience developing or running analytical methods for solubility viscosity osmolality aggregation stability or other developability assessments for complex oligonucleotide or antibody/protein formulations.
Familiarity with automation high-throughput screening and DoE-based formulation optimization is an advantage.
Strong experimental planning documentation data analysis and problem-solving skills.
Excellent verbal and written communication skills with the ability to work effectively across disciplines and functions.
Awareness of external trends and advances in RNA delivery oligonucleotide therapeutics and clinical translation is a plus.
A track record of scientific contributions publications or conference presentations in relevant areas is a plus.