Research Associate 2

Introduction:Xencor is a public clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our focus is developing high-potential XmAb bispecific T-cell engagers and additional engineered drug candidates that leverage our differentiated technology platforms and we are advancing our pipeline toward clinical proof-of-concept decisions. Our goal is to create high-impact therapeutics for patients with cancer and other serious diseases. More than 20 XmAb drug candidates engineered with our technology are in clinical development and three XmAb medicines have been marketed by partners. For more information please visit . We have an excellent opportunity for a Research Associate 2 in our Bioanalytical Development group to join our position is on-site at our Pasadena Ca. : Responsible for providing support and contributing to daily laboratory operations supporting efforts to identify and develop therapeutic antibody candidates using specialized methods specific to the assigned group function or Duties Include: Supports the development qualification and execution of immunoassays for the detection of anti-drug antibodies (ADA) pharmacokinetics (PK) and biomarkers in preclinical and clinical samples for therapeutic antibody and protein candidates in the areas of oncology inflammation and autoimmune disease. Contributes to research team efforts toward designing and running experiments analyzing results and interpreting data Documents experimental protocols designs and results in a laboratory notebookConducts and troubleshoots various experiments in support of researchExecutes standard operating proceduresMaintains laboratory inventory equipment and related suppliesUtilizes computer programs to collect analyze and record dataAnalyzes and reports data adhering to previously established timelinesCommunicates data to team membersContributes content to SOPs presentations and technical reportsMay present data in departmental meetingsFollows all laboratory safety guidelines practices and protocolsCoordinates and collaborates on research-related tasks across multiple groupsAdheres to all department and company-wide policies regarding conduct performance and proceduresPerforms other duties as minimally requires a High School diploma or GED with at least 6 years related laboratory work experience in an academic or industry setting. A Bachelors degree in biological sciences cell biology immunology or a related field with at least 3years related laboratory work experience is preferred. A Masters degree in biological sciences cell biology immunology or a related field with 1-2 years related laboratory work experience in an academic or industry setting is highly preferred. Industry experience is also preferred. Position also requires:Ability to adapt to changing prioritiesStrong interpersonal skillsStrong organizational skills and attention to detailAbility to work well in a team and independentlyStrong oral and written communication skillsAbility to work in a fast-paced goal-oriented multi-project environmentAbility to understand and follow instructions from supervisors or other team membersAbility to provide guidance to subordinate rolesDetail oriented good documentation practice and strong organizational skills; ability to perform method development with assistance follow and write basic lab protocols maintain detailed records and inventoryProficiency in MS Office (Word Excel Outlook PowerPoint) and ability to use job relevant software programs like GraphPad Prism JMP SoftMax MSD Discovery Workbench etc. Ability to demonstrate competencies applicable for job based on Xencors Leadership Competency on assigned research group certain Research Associate 2 positions may also require any or all of the following:Technical proficiency and experience developing and running immunoassays and/or bioassaysExperience in protein quantitation labelling and conjugation in the development and optimization of ELISA ECL (MSD) and other ligand-binding assays (LBA) for PK ADA and biomarker sample analysis under GLP-like conditions ensuring data accuracy and to method qualification troubleshooting and assay performance evaluationsExperiences in flow cytometry with proficiency in multi-laser flow cytometry preferredExperience applying complex multiple cell type co-culture techniques Experience with aseptic techniques such as may be required for working in BSCs. Experience with mammalian cell culture (aseptic preparation of media freezing and thawing of cells expanding/splitting cells for in vivo implantation). Prepare buffers reagents and detailed documentation including assay worksheets and experimental laboratory equipment and adhere to all safety and quality closely with scientists and cross-functional teams to support preclinical and clinical study in data interpretation reporting and presenting findings in internal Requirements for Laboratory and Research Related JobsThis role may involve work with experimental subjects and/or specimens including infected samples plus various Hazardous Materials and infectious agents (Bloodborne Pathogens or other potentially infections materials (OPIMs). Therefore the following are also required:Ability to follow the established Environmental Health & Safety rules procedures and/or BioSafety GuidelinesAbility to read and understand Safety Data Sheets (SDSs)Ability to be available and willing to work some weekends and evenings to conduct and complete experimentsKnowledge of biosafety techniques and aseptic/gowning practicesExperience with laboratory safety standards and procedures including biohazard handling and disposal techniques and the ability to ensure laboratory compliance with required safety regulationsExperience working with biological and chemical hazards infectious agents bloodborne pathogens and animal allergensExperience working in and maintaining a sterile environmentExperience working with chemical and biological hazards Thorough knowledge of the operation and maintenance of various lab equipment such as microscopes centrifuges spectrophotometers balances pH meters and electrophoresis equipment freezers and Base Salary Range: $80000 - $96000The actual salary will be based on the selected candidates qualifications including skills competencies education and offers a competitive total rewards package including 401k match healthcare coverage ESPP and a broad range of other addition this position will be eligible for an annual bonus and equity grant. For more information please see with Disabilities Act (ADA) StatementThe Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process please contact perform this job successfully an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential Employment Opportunity (EEO) StatementThe Company is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age race color religion sex sexual orientation gender or gender identity national origin disability status protected veteran status or any other characteristic protected by state or federal does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor implied or otherwise.