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Program Management Office Manager


Job Location:

Redwood City, CA - USA

Yearly Salary: USD 143000 - 178000
Posted: 29 September 2026 (20 hours ago)
Application Deadline: 27 December 2026
Vacancies: 1 Vacancy

Job Summary

Revolution Medicines is a global commercial-state oncology company dedicated to discovering developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform the company is advancing a broad integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active cancer-driving state of on rigorous scientific inquiry and a willingness to challenge long-held assumptions Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science challenge assumptions act with urgency and hold ourselves to a high standard of rigorall in service of patients.

The Opportunity:

Program Management Office (PMO) manager helps strengthen and scale program management capabilities across RevMeds development portfolio. This role will partner closely with Program Managers and cross-functional molecule teams to understand business needs and develop practical processes tools and ways of working that enable effective planning collaboration and execution. The ideal candidate combines strong program management fundamentals with a passion for operational excellence and continuous improvement. They will bring structure to complex problems translate the needs of Program Managers and molecule teams into scalable solutions and drive adoption of tools and processes that improve visibility consistency and effectiveness across programs. This is a highly collaborative role with the opportunity to help shape how Program Management operates as RevMeds portfolio and organization continue to grow. Key responsibilities include:

  • Partnering with Program Managers and molecule teams to identify opportunities to improve program planning execution communication and cross-functional ways of working.

  • Developing implementing and improving program management processes tools templates and standards that increase consistency and effectiveness across the development portfolio.

  • Supporting the development and adoption of integrated planning tools that provide visibility into key milestones dependencies risks decisions and program deliverables.

  • Gathering feedback from Program Managers and cross-functional stakeholders identify common challenges and emerging needs and translate those insights into practical PMO solutions.

  • Driving implementation and sustained adoption of new PMO capabilities by developing guidance training communications and resources.

  • Establishing metrics and feedback mechanisms to assess the effectiveness of PMO tools and processes and identify opportunities for continuous improvement.

  • Partnering across Development and other functions to align program management practices share best practices and ensure PMO capabilities evolve as RevMeds portfolio and organization grow.

Required Skills Experience and Education:

  • B.A. or BSc. with 8 years in Life Sciences or; an MSc with 6 years experience in a scientific or similarly related field.

  • Strong understanding of program management principles including integrated planning cross-functional execution milestone and critical path management risk and issue management dependencies and decision-tracking.

  • Working knowledge of the drug development lifecycle and the roles of key functions within a cross-functional development team.

  • Demonstrated ability to identify business needs and develop scalable processes tools templates and ways of working that improve team effectiveness and portfolio visibility.

  • Strong stakeholder management and influencing skills with the ability to build relationships gather diverse perspectives and facilitate alignment and naviage competing priorities across functions.

  • Ability to bring structure to ambiguous or complex problems identify root causes and translate needs into practical solutions.

  • Strong written and verbal communication skills with experience introducing new processes developing training or guidance and driving adoption.

  • Experience with change management and adoption including developing training communications or resources that help teams successfully adopt new tools and ways of working.

  • Comfort working with program management and collaboration platforms such as Smartsheet Microsoft 365 or similar tools with the ability to use data and metrics to identify opportunities for improvement.

Preferred Skills:

  • Experience working in a rapidly growing biotechnology or pharmaceutical R&D environment helping evolve processes from fit-for-purpose solutions into scalable organizational capabilities.

  • Familiarity with late-stage development regulatory submissions or commercialization readiness would be beneficial but not required.

  • Experience within a PMO Program Management Center of Excellence or similar enablement function focused on improving program management capabilities.

  • PMP PgMP Agile Lean/Six Sigma change management certification or similar professional training is a plus.

#LI-EM1 #LI-Hybrid

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role level and location. Individual base pay salary is determined by multiple factors including job-related skills experience market dynamics and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed which includes competitive cash compensation robust equity awards strong benefits and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race color religion gender sexual orientation gender identity/expression national origin/ancestry age disability marital status medical condition and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect process and use any personal data that you provide to us in accordance with ourCCPA additional information please contact.

Base Pay Salary Range

$143000 - $178000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms email phone or text message.

Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information purchase equipment or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @ email address.

If you believe youve been contacted by someone impersonating a Revolution Medicines recruiter please report it to so we can share these impersonations with our IT team for tracking and awareness.


Required Experience:

IC


About Company

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, ... View more

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