Process Development Associate Cambridge MA

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Associate

What you will do
Lets do this. Lets change the this vital role you will contribute towards Amgens Drug Substance Process Development for late stage clinical and commercial biologics programs including the development characterization and scale-up of upstream and downstream manufacturing processes supporting Ph II/III clinical trials to marketing application. This role is within an integrated organization in which cell culture and purification scientists work together to advance Amgens rich and dynamic pipeline. With Amgens biology first approach the position provides a unique opportunity to work on multiple modalities from antibodies to oncolytic viruses to bi-specifics.

The Process Development Associate will help design and perform experiments at the bench scale that span the end-to-end Drug Substance process from cell culture to purification this role you will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally the Process Development Associate will utilize out-of-the-box thinking to contribute to technology development and will demonstrate the desire to expand and develop expertise in both cell culture and purification thereby further contributing to the integrated group. The Process Development Associate will join a diverse team with varied levels of experience and report to a Process Development Principal Scientist.

Contribute within a project team on goals such as improving process yield and robustness and scaling-up processes to manufacturing sites

Perform small-scale bioprocess experiments that encompass both upstream (cell culture) and downstream (purification) operations

Cell culture responsibilities may include maintaining cultures in shake flasks culture bags and benchtop bioreactors

Purification experiments include but are not limited to protein chromatography filtration and UF/DF operations

Automation programming for benchtop bioreactors chromatography systems and robotic liquid handling systems

Experimental design and data interpretation leveraging in-house visualization and analytics tools

Communication of findings through oral presentations and written documentation (technical reports as well as GMP documents to support regulatory filings)

Provide scientific technical support for technology transfer of processes to manufacturing sites

What we expect of you
We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications.