Principal Research Scientist I, siRNA Platform Automation

AbbVies Biotherapeutics and Genetic Medicine (BGM) department is seeking a highly motivated Principal Research Scientist to join our expanding siRNA this role you will partner with genetic medicine teams to establish a high-throughput siRNA screening platform that advances pipeline innovation through next-generation delivery modalities and supports the discovery of therapeutic leads across multiple disease areas. 

Responsibilities:

• Establish and implement a high-throughput siRNA screening platform using automated liquid-handling systems. 
• Serve as a subject matter expert in siRNA screening experimental design execution and data interpretation. 
• Lead research efforts and mentor scientists to advance siRNA optimization including sequence design and novel chemical modifications across multiple programs. 
• Generate new scientific hypotheses and proposals improve existing screening workflows and evaluate emerging technologies in the siRNA field. 
• Communicate clearly and effectively with internal siRNA teams and cross-functional collaborators to identify needs and support platform enhancement and program advancement. 
• Manage and develop a team of at least 2-3 scientists providing technical guidance mentorship and day-to-day leadership to support program goals. 

Qualifications :

• BS MS or PhD in Molecular Biology Biochemistry Chemical Biology or a related field with typically 6 years (PhD) 12 years (MS) or 14 years (BS) of relevant experience in biotech or pharma.
• Proven track record in siRNA design in vitro screening and potency assays with experience using automated high-throughput platforms (e.g. Hamilton Tecan).
• Experience with assays including but not limited to qRT-PCR ELISA and flow cytometry.
• Demonstrated experience in cell culture including the maintenance of diverse cell lines.
• Prior experience leading siRNA platform initiatives or portfolio programs.
• Experience in animal study design and downstream assays to evaluate genetic medicines is a plus.
• Exceptional interpersonal skills and the ability to build productive working relationships with diverse internal teams and external collaborators.
• Strong track record of presenting complex scientific data to internal and external stakeholders.
• Prior people management experience is a plus.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future. 
• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term and long-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time