Principal Investigator

Position: Principal Investigator

Salary Range: $200 - $285k (DOE)

Location: Baltimore MD (On-site)

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25000 employees worldwide across 28 locations in the US UK China and Singapore we support drug discovery through to manufacturing with fully integrated high-quality services.

Were proud of the impact we make and just last year we supported 887 discovery projects 1100 CMC programs and 1397 clinical trials across all phases. Our teams are involved in everything from small molecules ADCs biologics and gene therapies and we work with more than 3300 global customers. To learn more visit .

Job Overview

Pharmaron is seeking an experienced physician to serve as a Principal Investigator within our growing Phase I Clinical Research Unit in Baltimore Maryland.

This is a unique opportunity for a board-certified physician who is passionate about advancing medicine through clinical research while maintaining a strong focus on participant safety and quality care. Clinical research experience is welcomed but not required. Physicians with backgrounds in Internal Medicine Family Medicine Emergency Medicine or related specialties are encouraged to apply.

As Principal Investigator you will provide medical leadership for early-phase clinical studies oversee participant safety collaborate with sponsors and scientific teams and help shape the future growth of our clinical research programs.

Key Responsibilities:

Clinical Leadership

• Serve as Principal Investigator or Sub-Investigator for Phase I-III clinical studies
• Provide medical oversight and ensure participant safety throughout study conduct
• Review eligibility medical histories adverse events and safety data
• Conduct physical examinations and medical assessments as required

Study Execution & Scientific Collaboration

• Partner with sponsors and internal teams on protocol review study design and implementation
• Support dosing activities and ongoing medical monitoring
• Contribute to study interpretation reporting and regulatory submissions
• Provide scientific and medical consultation to project teams and clients

Regulatory & Quality Oversight

• Ensure studies are conducted in compliance with ICH-GCP FDA regulations and applicable guidelines
• Maintain protocol integrity and oversight responsibilities as listed on FDA Form 1572
• Support inspections audits and regulatory interactions when required

Team Leadership

• Mentor and guide Clinical Research Coordinators nurses and study staff
• Promote a culture of participant safety quality and operational excellence
• Collaborate closely with Medical Clinical Operations Pharmacy Laboratory and Business Development teams

What Were Looking For:

Required Qualifications

• MD or DO degree from an accredited medical school
• Board Certification in a recognized specialty
• Active and unrestricted medical license
• Minimum 5 years of clinical practice experience
• Current CPR and ACLS certifications
• Strong understanding of patient care medical ethics and clinical decision-making
• Excellent communication and leadership skills

Preferred Qualifications

• Previous clinical research experience as a Principal Investigator Sub-Investigator or treating physician
• Experience supporting Phase I or early clinical development programs
• Familiarity with ICH-GCP FDA regulations and clinical trial operations
• DEA registration
• Background in Internal Medicine Family Medicine or Emergency Medicine

Why Pharmaron

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004 Pharmaron has invested in its people and facilities and established a broad spectrum of research development and manufacturing service capabilities throughout the entire drug discovery preclinical and clinical development process across multiple therapeutic modalities including small molecules biologics and CGT products. With over 21000 employees and operations in the U.S. the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America Europe Japan and China.

Collaborative Culture: You will thrive in our inclusive and collaborative environment where teamwork and innovation go hand in hand. Here your voice matters and your contributions make a real impact. Employees Number One and Clients Centered are the core cultural values at Pharmaron. Our culture which sets Pharmaron apart from other organizations has evolved from our deep commitment to our employees partners and collaborators.

Benefits: As part of our commitment to your well-being we offer a comprehensive benefits package:

• Insurance including Medical Dental & Vision with significant employer contributions
• Employer-funded Health Reimbursement Account
• Healthcare & Dependent Care Flexible Spending Accounts
• 100% Employer-paid Employee Life and AD&D Insurance Short- and Long-Term Disability Insurance
• 401k plan with generous employer match
• Access to an Employee Assistance Program

How to Apply:

Ready to seize this incredible opportunity Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

As an Equal Employment Opportunity and Affirmative Action employer Pharmaron values diversity and inclusion in the workplace fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Required Experience:

Staff IC