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Principal Electrical Engineering Architect

Seer


Job Location:

Redwood City, CA - USA

Monthly Salary: Not provided by the employer
Posted: 21 July 2026 (30+ days ago)
Application Deadline: 19 November 2026
Vacancies: 1 Vacancy

Job Summary

At Seer we are passionate about empowering our customers to expand scientific discoveries and achieve exceptional scientific outcomes. Our team is growing quickly as we develop innovative approaches to solve complex biological questions. And we believe the next frontier in biology is enabled through a clearer and more complete view of the proteome something that Seer can uniquely deliver. As we build our team we are looking for collaborative driven intellectually curious people who are committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe that this enables the kind of breakthrough thinking that will accelerate our mission.

The Role & The Team

This role will report to the Director of Systems Integration and join our team based in our Redwood Shores facility.

We are seeking a highly skilled Electrical Engineering Architect to lead the electrical design of a next-generation mass spectrometer for life sciences applications. This role requires deep technical expertise in managing the complex electromagnetic environments inherent to charged particle beam instrumentation. You will be responsible for architecting systems that demand extreme precision stability and immunity to noise ensuring optimal ion beam fidelity for advanced analytical workflows including liquid chromatography-mass spectrometry (LCMS).

Responsibilities&Goals

This special projects group is focused on using the latest product development and associated instrumentation for proteomics molecular profiling. Areas of specific responsibility and attention will include:

  • Architect the comprehensive electrical system layout for a novel TOF mass spectrometer.
  • Specify high-voltage DC power supply architecture (up to 15 kV) for precision ion optics and flight tubes.
  • Develop robust high-voltage RF systems (1-2 MHz 4 kV amplitudes) for ion guides funnels quadrupoles and traps. Ensure high stability and low temperature drift.
  • Implement rigorous grounding shielding and isolation strategies to mitigate RF pickup on lenses and signal lines.
  • Engineer component-level solutions to minimize electronic noise voltage ripple and thermal drift that negatively impact ion beam trajectories mass resolution and mass accuracy.
  • Oversee the integration of high-voltage electronics within high-vacuum systems and define system-level cabling and interconnect strategies.

Background&Qualifications

The successful candidate will have deep hands-on experience with mass spectrometry with expertise spanning sample preparations through data analysis. Candidates must bring a strong entrepreneurial orientation along with teamwork skills and commitment to competing with the highest level of integrity and engagement.

Requirements include:

  • Masters degree or Ph.D. in Electrical Engineering Applied Physics or a closely related discipline.
  • Minimum 10 years of experience in an academic or life-sciences industry laboratory setting (biotech start-up experience preferred).
  • Demonstrated architectural design experience with mass spectrometers electron microscopes focused ion beam systems particle accelerators or other similar technology.
  • Proven track record of designs implementing high voltage DC and high amplitude RF electronics.
  • Extensive practical knowledge of signal integrity ultra-low noise analog circuit design and precision timing circuits.
  • Deep understanding of the physical challenges associated with guiding low-energy ion beams without introducing phase-space distortion.
  • Strong written and oral communication skills with demonstrated experience in cross-functional and timely communication.
  • Strong and collaborative work ethic; must be a self-starter and persistent in achieving objectives to support Seers scientific and business goals.
  • Must work well in a small team setting with the ability to work independently and collaboratively while meeting scheduled deadlines in a fast-paced environment

Physical Requirements

  • Prolonged periods of sitting at a desk and working on a computer.
  • Prolonged periods of standing
  • frequently lift carry push pull or otherwise move objects with minimal force. Repetitive movements.
  • Ability to wear PPE for prolonged periods
  • Must be able to lift up to 15 pounds at times.

At Seer base pay is one part of our total compensation package and is determined within a range. This provides the opportunity to progress as you grow and develop within a role. The base pay range for this role is between $175000 and $205000 and will depend on the candidateseducation skills qualifications experience and location. This position is also eligible for bonus benefits and participation in Companys stock option plan.

#LI-Onsite

Seer is an equal opportunity employer that values diversity and inclusion. All applicants will be considered for employment without attention to race color national origin religion gender gender identity sexual orientation age marital status veteran status or disability you are interested in applying for employment and need special assistance or an accommodation to apply for a posted position contact our Human Resources department at. See also (Seers EEO Policy).

Seer is also an affirmative action employer has an affirmative action plan (AAP) and seeks to abide by all applicable state laws and regulations for applicant notifications. For questions about or to view Seers AAP including with respect to veterans and individuals with disabilities please reach out toto schedule a meeting. For additional information on applicant notifications please visit the links below:


Required Experience:

Staff IC


About Company

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Seer is a life sciences company focused on capturing deep molecular insights from the proteome to enable novel insights and breakthroughs in the understanding of biology and disease. Our novel Proteographâ„¢ platform allows for the first-ever generation of proteomic information with hig ... View more

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