Principal Data Architect, CMC Digital

The Role

The Principal Data Architect will design and steward the enterprise data architecture that makes CMC data usable governable and AI-ready at scale. This role defines integration patterns data models metadata standards and reusable architecture artifacts that enable consistent scalable delivery of data products across Manufacturing Quality and Supply Chain operations. A core focus is enabling the integration of real-time data from control systems and automation environments into a unified event-driven architecture that bridges OT and IT data requiring deep understanding of manufacturing and automation processes.

CMC data spans systems with diverse structures semantics and quality characteristics. This role brings coherence to that complexity by designing patterns that normalize heterogeneous data into a platform where analysts engineers and AI systems can operate with confidence. As a principal-level contributor this individual operates with significant autonomy influences technical direction across CMC Digital and builds the architectural foundations that enable consistent reusable and scalable data and AI capabilities across the enterprise.

Heres What Youll Do

Define and maintain the target-state data architecture across CMC domains designing for composability with shared entities modeled once and domain-specific extensions layered on top

Define and implement integration patterns that connect control systems and automation environments with enterprise data platforms enabling real-time event-driven data flows across OT and IT layers

Establish repeatable patterns for ingesting transforming and serving data from heterogeneous CMC systems

Define and enforce data standards including naming conventions classification lineage and metadata treating metadata as a first-class architectural concern

Design data models and semantic structures that support both analytics and AI use cases across CMC domains

Codify architecture patterns as templates reference implementations and decision records enabling teams to build from proven designs rather than starting from scratch

Develop strategies for controlled vocabularies business glossaries and semantic models that make CMC data consistent and navigable across domains

Inform cloud data platform decisions across warehousing transformation orchestration and catalog tooling to ensure alignment with architectural standards

Mentor engineers and data product owners raising architectural fluency and design consistency across the CMC Digital organization

Heres What Youll Need (Basic Qualifications)

Bachelors or Masters degree in Computer Science Engineering Data Science or a related field

7 years of experience in data architecture data engineering or enterprise architecture

4 years of experience supporting pharmaceutical biotech manufacturing or other regulated environments

Experience integrating data from control systems automation environments or real-time operational data sources

Experience designing data architectures that span operational systems and analytical platforms connecting source systems to governed reusable data products

Integration architecture experience across enterprise systems including ERP QMS MES LIMS or equivalent

Strong understanding of data modeling both dimensional and entity-relationship approaches applied to operational and analytical use cases

Proven ability to produce architecture specifications that engineering teams can implement directly

Strong understanding of data governance mechanics including lineage access control data classification and retention

Understanding of GxP data integrity and compliance considerations and how they shape architectural decisions

Heres What Youll Bring to the Table (Preferred Qualifications)

Direct experience with Veeva Quality LabVantage Syncade or similar MES and LIMS platforms and their data structures

Experience with OT/IT integration architecture including MES DCS SCADA or historian systems in a regulated environment

Familiarity with manufacturing data standards and how they inform enterprise data architecture decisions

Experience with SAP data domains and integration patterns for manufacturing and supply chain data

Hands-on experience with dbt Redshift Snowflake or similar transformation and cloud data warehouse tooling

Experience with metadata management data catalog tooling or business glossary programs at enterprise scale

Experience designing multi-schema or multi-tenant architectures with fine-grained policy-driven access control

Exposure to knowledge graphs ontologies or semantic modeling applied to enterprise or scientific data

Experience with GitHub-based workflows architecture-as-code practices or version-controlled specification and pattern management

Experience with or strong interest in AI-ready data architecture including how data models semantic layers and operational knowledge bases support agentic AI workflows

Background in GxP validation readiness for data platforms and how architectural decisions affect future compliance posture

Pay & Benefits

At Moderna we believe that when you feel your best you can do your best work. Thats why our benefits and well-being resources are designed to support youat work at home and everywhere in between.

• Competitive healthcare plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being with access to fitness mindfulness and mental health support
• Family planning benefits including fertility adoption and surrogacy support
• Generous paid time off including vacation volunteer days sabbatical global recharge days and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $145900.00 - $234200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individuals position within the salary range will be based on several factors including but not limited to specific competencies relevant education qualifications certifications experience skills performance and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus other incentive compensation or equity award subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine we invite you to visit to learn more about our current opportunities.

Our Working Model

As we build our company we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation teamwork and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.

Moderna is a smoke-free alcohol-free and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.

Accommodations

Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .

Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws including the Export Administration Regulations (EAR). As such employment is contingent upon the applicants ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements only individuals who qualify as U.S. persons (citizens permanent residents asylees or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-KH1

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