Postdoctoral Scholar, ADC Discovery Chemistry

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at .

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About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

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We are searching for the best talent for a Postdoctoral Scholar ADC Discovery Chemistry to be located in Spring House PA.

Purpose: The Postdoctoral Scholar ADC Discovery Chemistry will conduct independent research focused on the discovery and optimization of nextgeneration mechanisms for antibodydrug conjugates (ADCs). This role will integrate medicinal chemistry synthetic chemistry and bioconjugation to translate novel linker-payload constructs into biologically validated ADCs.

• Design synthesis and bioconjugation of novel linker-payload constructs.
  
• Applying medicinal chemistry principles to define structure-activity relationships and progress linker-payloads through DMTA cycles.
  
• Organizing scientific findings into clear summaries and communicate them to the broader ADC Discovery team.
  
• Participating in required trainings development activities internal meetings and scientific symposia.
  

Education:

• A PhD in Organic Chemistry Medicinal Chemistry Chemical Biology or a related field is required.
  

Required:

• Extensive experience and record of accomplishments in organic and/or medicinal chemistry including evidence of complex multistep syntheses.
  
• Ability to design experiments independently interpret complex datasets and draw scientifically sound conclusions.
  
• Strong project management skills and the ability to independently prioritize tasks in a complex fast-paced dynamic environment.
  
• Effective collaboration skills and comfort working in cross-functional multidisciplinary research teams.
  
• Exceptional written and verbal communication skills including the ability to present scientific findings clearly to diverse audiences.
  

• Prior research experience in ADCs linker-payload chemistry or targeted drug delivery.
  
• Experience with bioconjugation chemistry and ADC characterization (e.g. DAR analysis SEC HIC).
  
• Strong understanding of drug-like physicochemical properties and their effect on biological performance.
  

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

If you are under 18 years of age you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment as well as get a parents consent for the background check.

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