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Postdoctoral Research Fellow


Job Location:

Boston, MA - USA

Monthly Salary: Not provided by the employer
Posted: 23 May 2026 (30+ days ago)
Application Deadline: 30 September 2026
Vacancies: 1 Vacancy
The job posting is outdated and position may be filled

Job Summary

Site: The Brigham and Womens Hospital Inc.


Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.


Job Summary

Postdoctoral position available to study mechanisms of response to immune checkpoint inhibitors in kidney cancer.

Immunotherapy with immune checkpoint inhibitors (e.g. anti-PD-1/PD-L1 agents) has demonstrated clinical efficacy in metastatic renal cell carcinoma (mRCC). Unfortunately only a subset of mRCC patients responds to these agents. To guide further clinical development of immune checkpoint inhibitors in kidney cancer we aim to 1) develop and validate tissue-based predictors of drug response using both genomics approaches and in situ analyses; 2) understand the mechanism of action of PD-1/PD-L1 blockade to facilitate the development of highly active combination regimens.


Qualifications

The salary range for this position is $70000 to $ 71750 annually.

Requirements: We are seeking a highly motivated applicant with an M.D. or M.D./Ph.D. with formal training in Anatomic Pathology (at least 1 year in residency program) and laboratory experience in pathology and/or molecular biology. Background in bioinformatics/computational biology is desirable. Excellent written and oral communication skills are required. The candidate must be willing to commit to the position for at least two years.

If interested please send a cover letter CV and three references to:

Sabina Signoretti M.D.
Department of Pathology
Brigham and Womens Hospital
Thorn Building 504A
75 Francis Street
Boston MA 02115
(phone)


Additional Job Details (if applicable)


Remote Type

Onsite


Work Location

75 Francis Street


EEO Statement:

2200 The Brigham and Womens Hospital Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact Human Resources at .


Mass General Brigham Competency Framework

At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.


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Patients at Mass General have access to a vast network of physicians, nearly all of whom are Harvard Medical School faculty and many of whom are leaders within their fields.

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