Postdoctoral Associate- Xiao Wang Lab

The Xiao Wang group at the Broad Institute of MIT and Harvard is looking for an exceptional and energetic postdoctoral associate to join a rapidly growing multidisciplinary research focused on developing and applying molecular and imaging tools (e.g. in situ RNA sequencing) to understand the complexity of the biological systems.

This postdoctoral position will provide an exciting opportunity to develop new sequencing/imaging strategies for multiscale brain mapping in a vibrant and interdisciplinary environment and collaborate with team members from diverse backgrounds (chemistry biophysics genomics and neuroscience). We emphasize the research training and career development for all lab members and the candidate will have chances to interact with the research teams within Broad Institute and also the broader community in MIT Harvard and the Harvard-affiliated hospitals across Boston.

MINIMUM QUALIFICATIONS

0 years of postgraduate experience.

PhD in physical/biological science neuroscience bioengineering or related disciplines

Hands-on experience with microscopy molecular biology animal models and gene delivery vectors (e.g. AAV and lentivirus)

Self-motivated creative persistent responsible attention to detail good analytical and problem-solving skills fast learner

RESPONSIBILITIES

Fluorescence microscopy (living/preserved samples) electron microscopy (SEM/TEM) or CLEM (correlative light and electron microscopy)

Design and generate AAV or lentivirus vector for the expression of transgenes in desired subcellular locations and desired cell populations

Design characterization and engineering of RNA: e.g. in situ hybridization microarray gel electrophoresis HPLC SELEX NGS and single-cell RNA sequencing; RNA structure RNA modification/editing RNA localization RNA-protein complexes non-coding RNAs synthetic RNAs etc.

Scientific investigation in neuroscience or other biological systems at the molecular (nucleic acids proteins lipids) and cellular (subcellular organelles granules membranes synapses) levels