NGS Lab Scientist

You Will:

• Prepare tissues and primary cells for single-cell suspension

• Generate singlecellimmunoprofilinglibraries using 10x Genomics workflows including Gene Expression and TCR libraries

• Utilize laboratory automation platforms to support and streamline library preparation workflows

• Perform nextgeneration sequencing using IlluminaNovaSeqX Plus platforms

• Optimizeand troubleshoot assays to improve performance including deadcell removal and Tcell enrichment strategies

• Design execute and support NGSbased assays working both independently and in crossfunctional teams

• Contribute to data management and tracking usingelectronic laboratory notebooks (ELN)

• Manage multiple priorities to meet project timelines whilemaintainingaccurateexperimental records and clear communication of results

• Present findings and progress updates in internal and crossfunctional forum

• Supportadditionalactivities as needed to advance broader team and organizational objectives

You Have:

• Five (5) years with BS/BA or two (2) years with MS/MA in immunology cellular or molecular biology or in a relevant discipline with related lab or industry experience

• Background in genomics and molecular biology

• Hands-on experience with NGS library preparation

• Proficiencywith single-cell NGS platforms (10X Genomicsplatform)

• Experience with using Illumina sequencers (NovaSeqXPlus)

• Experience with laboratory automation platforms for library preparation (10X Chromium Connect and/or BeckmanBiomeki7

• Experience with preparation of primary cells for single-cell suspension

• Well-versed in cell culture aseptic techniques

• Organizational and record-keeping abilities

• Team-oriented attitude with the capability to work independently and in collaboration

• Open to taking on temporary responsibilities beyond theinitialjob description

Essential QualificationsSkillsand Experience

• Bachelors degree (BS/BA) with at least five years orMastersdegree (MS/MA)with at least two yearsof relevant laboratory or industry experience in immunology cellular or molecular biology or a related discipline.

• Demonstrated hands-on experience with next-generation sequencing (NGS) library preparation and single-cell NGS platforms (e.g. 10x Genomics).

• Proficiencyin using Illumina sequencers (NovaSeqX Plus) and laboratory automation platforms (such as 10X Chromium Connect and/or BeckmanBiomeki7).

• Strong organizational and record-keeping skills including experience with electronic laboratory notebooks (ELN).

• Ability to manage multiple priorities meet project timelines andmaintainaccurateexperimental records.

• Effective communicator able to present findings and progress updates in internal and cross-functional forums.

• Team-oriented attitude with the capability to work independently and collaboratively.

• Flexibility to take on temporary responsibilities beyond theinitialjob description.

Technical & Scientific Expertise

• Preparation of tissues and primary cells for single-cell suspension.

• Generation ofsingle-cellimmunoprofilinglibraries using 10x Genomics workflows including gene expression and TCR libraries.

• Optimization and troubleshooting of assays to improve performance including deadcell removal and T-cell enrichment strategies.

• Execution and support of NGS-based assays both independently and as part of cross-functional teams.

• Experience with cell culture aseptic techniques and preparation of primary cells for single-cell analysis.

• Familiarity with laboratory automation platforms to streamline library preparation workflows.

• Data management and tracking using ELN systems.

Domain Experience

• Background in genomics and molecular biology with practical experience in clinicaland commercial production environments.

• Experience working with multi-omicdata sets from clinical trials supporting bioinformatic research efforts.

• Exposure toCell therapy andimmunoprofilingapplications particularly within a clinical or translational research setting.

• Understanding ofoperational workflows in a regulated laboratory environment including compliance with quality standards.